Murti, Krisna and Mirani, Putri and Lestari, Peby Maulina and Liberty, Iche Andriyani and Andrina, Hana and Kesty, Cindy and Stevanny, Bella (2023) The Role of Vitamin D and Vitamin D Receptor in Placenta Accreta Spectrum: A Literature Review. Indonesian Journal of Obstetrics & Gynecology Science, 6 (1). pp. 20-27. ISSN 2615-496X
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Abstract
Objective: This study aims to review the role of vitamin D and vitamin D receptor in Placenta Accreta Spectrum Disorder (PASD) Method: This review used several databases, namely Google Scholar, Science Direct, Elsevier, Medline, PubMed, Proquest, dan Wiley Online Library to search original and review articles in English about placenta accreta spectrum, placenta accreta, vitamin D, and vitamin D receptor in the last 10 years. Other reference sources used were guidelines and textbooks. Results: A total of four articles were included in this review. Discussion: Placenta accreta spectrum disorder is becoming more common around the world, owing to the rise in cesarean deliveries. It is linked to several risk factors, including a lack of vitamin D. Vitamin D and its receptor stimulate endometrial decidualization, which aids implantation. Vitamin D receptors in human placental trophoblasts create and respond to 1,25(OH)2D3, which promotes the conversion of endometrial cells to decidual cells. Women with PASD are mostly suffering from vitamin D deficiency. Conclusion: Vitamin D levels may influence trophoblast invasion in PASD and can be a potential diagnostic marker. Key words: placenta accreta, vitamin D, vitamin D receptor
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) |
| Divisions: | 04-Faculty of Medicine > 11718-Pathology Anatomy (Sp |
| Depositing User: | dr., Ph.D. Krisna Murti |
| Date Deposited: | 11 May 2023 15:25 |
| Last Modified: | 11 May 2023 15:25 |
| URI: | http://repository.unsri.ac.id/id/eprint/101974 |
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