Riyanto, Riyanto (2017) PENGARUH EKSTRAK KULIT JERUK PURUT (Citrus hystrix DC.) TERHADAPPENURUNANKADAR ASAM URAT MENCIT JANTAN (Mus musculusL.) YANG DIINDUKSI KALIUM BROMAT DAN SUMBANGANNYA PADA PEMBELAJARAN BIOLOGI SMA. Jurnal Pembelajaran Biologi FKIP Unsri, 4 (1). pp. 15-27. ISSN 2355-7192
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Abstract
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak kulit jeruk purut terhadap penurunan kadar asam urat mencit. Metode yang digunakan adalah metode eksperimen dengan Rancangan Acak Lengkap menggunakan 24 ekor mencit jantan. Penelitian ini terdiri atas empat perlakuan dan enam ulangan. Perlakuan berupa pemberian aquades (kontrol) dan tiga tingkatan dosis yang terdiri dari 1,25 mg/10 gBB (P1), 2,5 mg/10 gBB (P2), dan 5 mg/10 gBB (P3). Data dianalisis dengan perhitungan analisis keragaman dilanjutkan dengan uji Beda Nyata Jujur (BNJ). Hasil yang didapat rata-rata kadar asam urat dari penelitian ini adalah 1,8 mg/dL pada dosis 5 mg/10gBB (P3) sebagai pengaruh paling tinggi dan 4 mg/dL pada dosis 1,25 mg/10gBB (P1) sebagai pengaruh paling rendah. Analisis Keragaman menunjukkan bahwa ekstrak kulit jeruk purut berpengaruh sangat nyata dalam menurunkan kadar asam urat mencit. Uji Beda Nyata Jujur (BNJ) menunjukkan bahwa terdapat dosis ekstrak kulit jeruk purut yang efektif untuk menurunkan kadar asam urat mencit yaitu dosis 5 mg/10gBB. Berdasarkan penurunan kadar asam urat yang terjadi dapat disimpulkan bahwa ekstrak kulit jeruk purut dapat menurunkan secara signifikan kadar asam urat mencit. Informasi hasil penelitian ini dijadikan masukan materi pembelajaran Biologi di SMA kelas X semester II pada Materi Pokok Kingdom Plantae khususnya Kompetensi Dasar 3.3 Mendeskripsikan ciri-ciri Divisio dalam Dunia Tumbuhan dan peranannya bagi kelangsungan hidup di Bumi. Kata Kunci: Ekstrak kulit jeruk purut, kadar asam urat, mencit Abstract: This study aimed to determine the effect of lime peel extract to reduce uric acid levels of mice. The method used was experimental method with the complete randomized design using 24 male mice. This study consisted of four treatments and six repetitions. Treatment for the provision of distill water (control) and three dose levels consisting of 1,25 mg/10 gBB (P1),2,5 mg/10 gBB (P2), dan 5 mg/10 gBB (P3). The data were analyzed by doing the analysis of variance followed by computation test of Honestly Significant Difference (HSD).The obtained results showed that the average uric acid levels of this study were 1,8 mg/dL at a dose of 5 mg/10 gBB (P3) as the highest impact and 4 mg/dL at a dose of 1,25 mg/10 gBB (P1) as the lowest effect. Diversity analysis showed that the lime peel extract has the significant impact in reducing of uric acid levels of male mice. Honestly Significant Difference test (HSD) showed that there was a dose of lime peel extracts which is effective in reducing uric acid levels in mice; it was a dose of 5 mg/10 gBB. Based on the reduction of the uric acid levels, it could be concluded that lime peel extract could significantly reduce uric acid levels in mice. Information of the result in this study could be the input learning materials of Biology subject for the tenth senior high school students in the second semester on the Plantae Kingdom topic especially in competency 3.3 which explains about describing Divisio?s characteristics in the Plantae Kingdom and its role for the life survival on earth. Keywords:Lime peel extract, uric acid levels, mice
| Item Type: | Article |
|---|---|
| Additional Information: | - |
| Uncontrolled Keywords: | Ekstrak kulit jeruk purut, kadar asam urat, mencit |
| Subjects: | L Education > L Education (General) > L7-991 Education (General) Q Science > Q Science (General) > Q1-295 General |
| Divisions: | 06-Faculty of Education and Educational Science > 84205-Biology Education (S1) |
| Depositing User: | Riyanto Riyanto |
| Date Deposited: | 09 Oct 2019 06:27 |
| Last Modified: | 17 Oct 2019 08:16 |
| URI: | http://repository.unsri.ac.id/id/eprint/10433 |
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