Riyanto, Riyanto (2003) Efek Asam Metoksiasetat (MAA) Terhadap Perkembangan Embrio Tahap Praimplantasi Mencit (Mus musculus) Swiss Webster. Majalah Ilmiah Sriwijaya, 36 (1). pp. 67-72. ISSN 0126-4680
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Abstract
The effects of methoxyacetic acid on preimplantation stage embryos of Swiss Webster mice (Mus musculus) have been studied. Female mice were superovulated with 5 I.U. of PMSG (Folligon) and 5 I.U. of hCG (Chorulon) and were mated with male mice overnight. A veginal plug detected at the following morning was confirmed as day 0 of gestation. On gestation day 2, mice were administered with MAA dose 2.5 mmol/kg bw by gevage. On gestation day 3.5 mice were sacrificed for embryo collection. The result showed that MAA could decrease significantly (p<0,05) the number of embryos that reached late blastocysts, this was caused by significant increase (p<0,05) of the percentege of embryos that could only reach the morula stage. It could be concluded, that the administration of MAA on gestation day 2 inhibit the developmental of preimplantation embryos, proven by the decrease of percentage of embryos that reached late blastocysts stage caused by developmental retardation, especially on the morula stage.
Item Type: | Article |
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Additional Information: | sifat teratogenik MAA terhadap embrio mencit |
Uncontrolled Keywords: | Asam Metoksiasetat (MAA), Embrio dan Mencit |
Subjects: | Q Science > QL Zoology > QL1-991 Zoology |
Divisions: | 06-Faculty of Education and Educational Science > 84205-Biology Education (S1) |
Depositing User: | Riyanto Riyanto |
Date Deposited: | 09 Oct 2019 03:49 |
Last Modified: | 09 Oct 2019 03:49 |
URI: | http://repository.unsri.ac.id/id/eprint/10469 |
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