Standardization of Ethanolic Extract of Tahongai Leaves (Kleinhovia hospita L.) (ARTIKEL)

Herlina, Herlina (2023) Standardization of Ethanolic Extract of Tahongai Leaves (Kleinhovia hospita L.) (ARTIKEL). Science and Technology Indonesia, 3 (1). pp. 14-18. ISSN 2580-4391

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Abstract

Extract is basic material for herbal drug. Herbal drugs formulation requires consistent of biological activity, a consistent chemical pro-file, or simply a quality assurance programs that can be achieved by standardizing the extracts. The leaves of tahongai (Kleinhovia hospita L.) have been traditionally used in Komering ethnic groups as phytotherapy to cure the inflammation related diseases including cancer, furuncles, polyps, and tonsillitis. The aim of this study was to standardize the quality of  ethanolic extract of tahongai leaves by determining the specific and non specific parameters of the extract. The preliminary phytochemical analysis revealed presence of alkaloids, flavonoids, saponins, tanins, and steroids in the extract. The result of specific parameters analysis of the extracts showed that the organoleptic properties of ethanolic extract of tahongai leaves were thick, brownish black, has distinctive odor, astringent with slightly bitter taste, the water and ethanol soluble extractive content were 19.263% ± 0.95 and 18.30% ± 0.51 respectively. The nonspecific parameters analysis of the extract showed that the extract’s density was 1.413 g/mL ± 0.04, the water content value was 21.16% ± 0.55, total ash content was 15.64% ± 0.75, acid insoluble ash content was 8.282% ± 0.28, Pb contamination content was 3.67 ppm, Cd contamination content was <0,0043 ppm, total bacteria contamination was 90.5 x 101 colony/g, and the total mold and yeast contamination was 1 x 101 colony/g.

Item Type:	Article
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) R Medicine > RS Pharmacy and materia medica > RS189-190 Assay methods. Standardization. Analysis
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Herlina Herlina
Date Deposited:	09 Jun 2023 12:49
Last Modified:	09 Jun 2023 12:49
URI:	http://repository.unsri.ac.id/id/eprint/107739

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