Yuwono, Yuwono (2010) EFFECT OF D543N AND TGTG DELETION 3? UTR Nramp1 GENE POLYMORPHISMS AGAINST PULMONARY TUBERCULOSIS AT MELAYU ETHNIC OF SOUTH SUMATERA. In: International Eijkman Institute and NEHCRI Joint Symphosium, 13 - 15 Desember 2010, Hotel Borobudur Jakarta.
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Abstract
Pulmonary tuberculosis is still a major health problem with incidence on the world each year 139/100000 population and caused 1,8 million people death.Immunological finding showed that only 10% of population infected by Mycobacterium tuberculosis will get pulmonary tuberculosis, 90% were not get the disease. It is indicated that genetic factors controlling immune responses have major role in the pathogenesis of tuberculosis. Some studies showed 3 kind of genes have major contribution: Mbl gene encoding surface protein in attachment process. Nramp1 gene encoding protein in phogolysosome, responsible for phagocytosis process and Vdr gene encoding protein that regulate cellular immunity.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) |
| Divisions: | 04-Faculty of Medicine > 11201-Medicine (S1) |
| Depositing User: | Yon Yuwono |
| Date Deposited: | 18 Oct 2019 04:45 |
| Last Modified: | 18 Oct 2019 04:45 |
| URI: | http://repository.unsri.ac.id/id/eprint/11142 |
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