OKTAVIANA, NAZHIFAH and Wijaya, Dina Permata and Miksusanti, Miksusanti (2023) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SUBMIKRO PARTIKEL EKSTRAK DAUN GINSENG JAWA (TALINUM PANICULATUM (JACQ.) GAERTN) DENGAN VARIASI KONSENTRASI KALSIUM KLORIDA TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS. Undergraduate thesis, Sriwijaya University.
![[thumbnail of RAMA_48201_08061381924070.pdf]](http://repository.unsri.ac.id/style/images/fileicons/text.png) |
Text
RAMA_48201_08061381924070.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy |
|
Text
RAMA_48201_08061381924070_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (4MB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB) |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (594kB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (845kB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (526kB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (378kB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (481kB) | Request a copy |
|
Text
RAMA_48201_08061381924070_0018019204_0023076802_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy |
Abstract
Javanese ginseng leaves (Talinum paniculatum (Jacq.) Gaertn) contains flavonoid compounds, one of which is quercetin as an antibacterial. This study aims to determine the variation in calcium chloride concentration as a crosslinker against the submicro particles produced and determine its antibacterial ability compared to Javanese ginseng leaf extract without polymers. Making submicro particles using the ionic gelation method by dispersing Javanese ginseng leaf extract into chitosan solution, then done drop by drop of sodium alginate and calcium chloride. The best formula is determined based on the highest %EE value, followed by particle characterization, stability test of the heating-cooling cycle method, and antibacterial activity test by disc paper diffusion method. The results of %EE formula 1, 2, and 3 were 89.796 %, 92.793 %, and 89.267 % respectively. The best formula characterization result (F2) shows a particle size of 538.4 nm; PDI 0.434; and zeta potential +15.9 mV. The results of the F2 stability test showed a decrease in percent levels by 4.121%. The results of the F2 antibacterial activity test showed antibacterial activity against Staphylococcus aureus with an inhibitory zone diameter of 22.00 mm ± 1.00 (strong category). It can be concluded that submicro particles of Java ginseng leaf extract have fairly good characterization and stability, as well as a greater antibacterial activity than unformulated Java ginseng leaf extract.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Uncontrolled Keywords: | Daun Ginseng Jawa, Kalsium Klorida, Submikro Partikel, Staphylococcus aureus |
| Subjects: | Q Science > QR Microbiology > QR75-99.5 Bacteria R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) R Medicine > RS Pharmacy and materia medica > RS192-199 Pharmaceutical technology |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1) |
| Depositing User: | Nazhifah Oktaviana |
| Date Deposited: | 08 Aug 2023 03:09 |
| Last Modified: | 08 Aug 2023 03:09 |
| URI: | http://repository.unsri.ac.id/id/eprint/126268 |
Actions (login required)
 |
View Item |