HUBUNGAN KADAR HEMOGLOBIN, TROMBOSIT, DAN NEUTROPHIL LYMPHOCYTE RATIO DENGAN STADIUM KLINIS KANKER SERVIKS

SYAHBIRAN, HANIF GUSNERI and Sari, Nurmalia Purnama and Liana, Phey (2023) HUBUNGAN KADAR HEMOGLOBIN, TROMBOSIT, DAN NEUTROPHIL LYMPHOCYTE RATIO DENGAN STADIUM KLINIS KANKER SERVIKS. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Cancer is a medical condition characterized by rapid growth, spreading to surrounding tissue, and being able to spread to other more distant organs (metastasis). Cervical cancer occurs when abnormal cells in the cervix grow uncontrolled. Worldwide, the death rate for cervical cancer is 13.3/100,000 in 2020, which is caused by the majority being diagnosed in the terminal stage due to limited access to early detection and prevention. In cancer cases, there is often a decrease in hemoglobin (anemia), an increase in platelets and neutrophil lymphocyte ratio. This study aims to analyze the relationship between hemoglobin, platelet, and neutrophil-lymphocyte ratio levels with the clinical stage of cervical cancer. Methods: The type of research used is analytic observational with a correlation approach. The samples in this study is medical record data of patients diagnosed with Cervical Cancer aged ≥ 18 years at RSUP Dr. Mohammad Hoesin Palembang from August 2022 to July 2023 which meets the inclusion and exclusion criteria. Sampling is carried out by total sampling. Results: There were 153 samples that met the inclusion and exclusion criteria. Significant differences in levels of hemoglobin, leukocytes, neutrophils, platelets, and NLR between early and advanced stages of cervical cancer (p<0.001, p=0.001, p<0.001, p<0.001, p<0.001). A significant correlation was found between hemoglobin levels, platelets, and the neutrophil-lymphocyte ratio with the clinical stage of cervical cancer (r=-0.419, p<0.001; r=0.315, p<0.001; r=0.313, p<0.001). Conclusion: There was an association of hemoglobin, platelets, and neutrophil lymphocyte ratio with clinical stage of cervical cancer. Key words: hemoglobin, platelet, neutrophil lymphocyte ratio, cervical cancer

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Hemoglobin, trombosit, neutrophil lymphocyte ratio, kanker serviks
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Hanif Gusneri Syahbiran
Date Deposited:	18 Dec 2023 02:24
Last Modified:	18 Dec 2023 02:24
URI:	http://repository.unsri.ac.id/id/eprint/133203

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