PERBEDAAN PROFIL HEMATOLOGI PADA PASIEN KARSINOMA NASOFARING SEBELUM DAN SETELAH KEMOTERAPI DI KLINIK THT-BKL RSUP DR MOHAMMAD HOESIN PALEMBANG

WAHYUDI, FATHAN JORDAN and Ghanie, Abla and Utama, Denny Satria (2023) PERBEDAAN PROFIL HEMATOLOGI PADA PASIEN KARSINOMA NASOFARING SEBELUM DAN SETELAH KEMOTERAPI DI KLINIK THT-BKL RSUP DR MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Nasopharyngeal carcinoma (KNF) is a malignant tumor of the epithelium that affects the part of the throat connecting the back of the nose to the back of the mouth (pharynx). Chemotherapy is a common therapy option for people with advanced KNF. It is known that side effects that can arise in patients undergoing chemotherapy are nausea, vomiting, myelosuppression, anemia, and renal impairment. The purpose of this study was to determine whether there are differences in hematological profile of nasopharyngeal carcinoma patients before and after chemotherapy in ENT-HN clinic RSUP Dr. Mohammad Hoesin Palembang. Method: This study is an observational analytical study with quasi-experimental study design. Samples were taken using secondary data from the medical records of KNF patients at Dr. Mohammad Hoesin Palembang and taken by total sampling technique that is all samples obtained and meet the inclusion criteria were included in the study. Results: KNF patients at ENT-HN clinic RSUP Dr. Mohammad Hoesin were most commonly found at the age of 48–57 years (45.8%), more common in men (62.5%) and most often found in stage IVA (43.8%). There were significant differences in hemoglobin level (p<0.001), erythrocyte count (p<0.001), leukocyte count (p<0.001), and platelet count (p<0.001) before and after chemotherapy. There were no significant differences in the levels of urea (p=0.339) and creatinine (p=0.460) before and after chemotherapy. Conclusion: There are significant differences between hemoglobin level, erythrocyte count, leukocyte count, and platelet count and there are no significant differences between urea and creatinine levels in nasopharyngeal carcinoma patients before and after chemotherapy at ENT-HN clinic RSUP Dr. Mohammad Hoesin Palembang.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Karsinoma nasofaring, profil hematologi, kemoterapi
Subjects: R Medicine > R Medicine (General) > R5-920 Medicine (General)
R Medicine > RF Otorhinolaryngology > RF341-437 Rhinology. Diseases of the nose, accessory sinuses, and nasopharynx
Divisions: 04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User: Fathan Jordan Wahyudi
Date Deposited: 22 Dec 2023 07:50
Last Modified: 22 Dec 2023 07:50
URI: http://repository.unsri.ac.id/id/eprint/136896

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