Anticariogenic Effect of Gambir (Uncaria Gambir [Roxb.]) Extract on Enamel Tooth Surface Exposed by Streptococcus mutans

Dewi, Siti Rusdiana Puspa and Kamaluddin, Muhammad Totong and Theodorus, Theodorus and Pambayun, Rindit (2016) Anticariogenic Effect of Gambir (Uncaria Gambir [Roxb.]) Extract on Enamel Tooth Surface Exposed by Streptococcus mutans. International Journal of Research in Health Sciences a Open Access Journal in Health Sciences, 6 (8). pp. 171-179. ISSN 2249-9571

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Abstract

Introduction: Dental caries is the most common problem in many nations in the world, especially in Indonesia. Elimination of bacteria as one of caries causal can be done in many ways; one of them is using gambir plant extract. Gambir has chemical compounds like catechin and tannin, which have anticariogenic effect. The aim of this study was to determine anticariogenic effect of gambir extract on enamel tooth surface exposed by Streptococcus mutans. Materials and Methods: An experimental study, in vitro, had been conducted in Integrated Laboratory Pasca Sarjana Unsri, Province’s Health Laboratory of South Sumatera, dan Metalurgy’s Laboratory of Engineering Faculty of University of Indonesia, and held on March to April 2015. There were 35 maxillary first premolar samples and divided into 5 groups; each groups using 40%, 50%, 60% gambir extracts, negative control or placebo, and positive control (using cefadroxil 500mg). Data were analyzed by using SPSS 22 vers. Results: The results showed that 60% gambir extract had equal effect of reducing the decline of micropores in enamel topography to cefadroxil 500 mg, 50% gambir extract had equal effect in reducing the decline of calcium’s weight to cefadroxil 500 mg and had dose-dependent effect, 40% gambir extract had equal effect in lowering colonies of Streptococcus mutans to cefadroxil 500 mg, and had dose-dependent effect. Conclusion: It can be concluded that 60% gambir extract has equal anticariogenic effect to cefadroxil 500 mg

Item Type:	Article
Uncontrolled Keywords:	dental caries, micropores, enamel topography, bacterial colonies, gambir extract.
Subjects:	R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Siti Dewi
Date Deposited:	04 Jun 2024 00:53
Last Modified:	04 Jun 2024 00:53
URI:	http://repository.unsri.ac.id/id/eprint/144831

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