The Antibacterial Efficacy of Miana LeavesExtractagainst Streptococcus Mutans

PUTRI, KHOFIFA ARDA ANGGELINA and Hestiningsih, Tyas and Ajiedarmo, Ibnu and Idayani, Novita and Dewi, Siti Rusdiana Puspa (2023) The Antibacterial Efficacy of Miana LeavesExtractagainst Streptococcus Mutans. The Antibacterial Efficacy of Miana LeavesExtractagainst Streptococcus Mutans, 4 (2). pp. 36-43. ISSN 2746-0592

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Abstract

Introduction:Streptococcus mutansis the main bacterium that causes dental caries. Miana leaves antimicrobial compounds such as flavonoids, alkaloids, tannins, and saponins are expected to have antibacterial properties against the growth of Streptococcus mutans. Purpose:To determine the antibacterial effect of miana leaves extract on Streptococcus mutansgrowth. Methods: This study was an in vitro laboratory experimental study with a post-test only control group design. The treatment groups consisted of Miana leavesextract using concentrations of 3,125%, 6,25%, 12,5%, and 25%, positive control (0.2%chlorhexidine) and negative control (dimethyl sulfoxide/DMSO).Inhibition zone test was done using disc diffusion method. Results: The results showed that each concentration of Miana leavesextract had antibacterial properties. The largest diameter of the inhibitory zone was at 25% concentration,but significant smaller than 0.2% chlorhexidine. Conclusion: Miana leavesextract had an antibacterial effect against Streptococcus mutans.

Item Type:	Article
Uncontrolled Keywords:	Antibacterial;Miana leaves;Streptococcus mutans
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Siti Dewi
Date Deposited:	04 Jun 2024 00:57
Last Modified:	04 Jun 2024 00:57
URI:	http://repository.unsri.ac.id/id/eprint/144835

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