PERBANDINGAN SITOTOKSISITAS ANTARA CALCIUM SILICATE DAN EPOXY RESIN-BASED SEALER PADA PERAWATAN SALURAN AKAR (SYSTEMATIC REVIEW)

SUARSYAF, HANA ZAKIYYAH and Yulianti, Rinda and Sujatmiko, Billy (2024) PERBANDINGAN SITOTOKSISITAS ANTARA CALCIUM SILICATE DAN EPOXY RESIN-BASED SEALER PADA PERAWATAN SALURAN AKAR (SYSTEMATIC REVIEW). Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Epoxy resin-based sealer is the gold standard sealer because of its good physical properties. However, epoxy resin sealer has the potential for cytotoxicity which can inhibit the healing process of periapical tissue. Calcium silicate-based sealer is an alternative sealer because of its more biocompatible properties. Objectives: This study aimed to compare cytotoxicity between calcium silicate and epoxy resin-based sealers in root canal treatment. Method: The study used PubMed, Google Scholar, and Science Direct databases for the last 5 years calculated from 2019-2024. The journals used were by the inclusion and exclusion criteria, then bias analysis was carried out and summarized to determine the cytotoxicity of calcium silicate and epoxy resin-based sealer. Result: This study successfully synthesized 19 in vitro journals with low bias results in 16 journals and 3 journals with moderate bias. In general, calcium silicate-based sealers have lower cytotoxicity than epoxy resin-based sealers with the explanation that the composition, conditions, and exposure time of the material play an important role in the biological properties of the sealer. Conclusion: Calcium silicate-based sealers exhibit lower cytotoxicity than epoxy resin-based sealers.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Calcium silicate, epoxy resin, cytotoxicity, biocompatibility
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Hana Zakiyyah Suarsyaf
Date Deposited:	23 Aug 2024 07:56
Last Modified:	23 Aug 2024 07:56
URI:	http://repository.unsri.ac.id/id/eprint/155913

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