Setiawan, Arum and Sagi, Mammed and Asmara, Widya and Istriyati, Istriyati (2011) Analisis Kuantitatif Sel Purkinje Cerebellum Mencit (Mus musculus L.) setelah Induksi Ochratoksin A Selama Periode Organogenesis. Jurnal Biota, 16 (2). pp. 262-268. ISSN 0853-8670
Preview |
Text
jurnal_biota_arum_setiawan.pdf - Published Version Download (189kB) | Preview |
Abstract
This study aims to determine the number of Purkinje cells of mice cerebellum of pups after induction of Ochratoxin A during organogenesis period. Thirty pregnant mice were divided randomly into 5 groups of 6. Ochratoxin A was dissolved in sodium bicarbonate, and administered orally on seventh to fifteenth days of gestation at dosage of 0.5, 1.0, 1.5 mg/kg bw. The remaining animals were used as an untreated control, and placebo were given by Sodium Bicarbonate. Dams were maintained until delivery. At 21 days of age, the offspring were sacrificed and taken his brain. Brains of mice subsequently prepared by parafin method and stained using Haematoxylin Eosin staining. Data Analysis using one way ANAVA and DMRT for the significance. The results showed that Ochratoxin A given to pregnant mice during the period of organogenesis causes impaired growth of Purkinje cells of mice treated with the more marked decline in the number of Purkinje cells compared with control and placebo. Key words: Cerebellum, ochratoxin a, purkinje cells
| Item Type: | Article |
|---|---|
| Additional Information: | Jurnal Nasional Terakreditasi |
| Subjects: | Q Science > QL Zoology Q Science > QL Zoology > QL700-739.8 Mammals Q Science > QL Zoology > QL951-991 Embryology |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1) |
| Depositing User: | Dr Arum Setiawan |
| Date Deposited: | 21 Nov 2019 04:00 |
| Last Modified: | 19 Nov 2022 14:31 |
| URI: | http://repository.unsri.ac.id/id/eprint/17397 |
Actions (login required)
 |
View Item |