UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA LINN) PADA TIKUS PUTIH JANTAN GALUR WISTAR

MARLIANI UMAIRO, RIRIN and Herlina, Herlina and Solihah, Indah (2019) UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA LINN) PADA TIKUS PUTIH JANTAN GALUR WISTAR. Undergraduate thesis, Sriwijaya University.

[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_01_FRONT_REF.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_01_FRONT_REF.pdf - Accepted Version
Available under License Creative Commons Public Domain Dedication.

Download (1MB)
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_02.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_02.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (347kB) | Request a copy
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_03.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_03.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (309kB) | Request a copy
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_04.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_04.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (412kB) | Request a copy
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_05.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_05.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (85kB) | Request a copy
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_06_REF.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_06_REF.pdf - Bibliography
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (278kB) | Request a copy
[thumbnail of RAMA_48201_08061181419030_0003077102_0008038802_07_LAMP.pdf] Text
RAMA_48201_08061181419030_0003077102_0008038802_07_LAMP.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (1MB) | Request a copy

Abstract

Kirinyuh leaves (Chromolaena odorata Linn) is a plant including to the family of asteraceae. Flavonoid compound has the potential to inhibit the enzyme xantin oxidase as catalyst for establishment of uric acid. This study purpose to determine of the antihyperuricemia activity of kirinyuh leaves ethanol extract in male white rats previously with high purine food. Parameters seen are the number of percent decrease uric acid levels to white male rats. The test animals divided into 5 groups is positive control, negartive control and group test with therapy dose 175 mg / Kg/BB, 350 mg / Kg/BB and 700 mg / Kg/BB. High purine food induction was performed on the whole group except normal group. Induction is done per oral every day with volume of administration calculated based on the weight of each male white rats. Test results showed a significant decrease in uric acid levels (P<0,05) of each dose variation in the test group. The higher the dose of kirinyuh leaves ethanol extract then the higher the level of uric acid in the body of the test animals. The value of ED50 from kirinyuh leaves ethanol extract (EEDA) is 216,074 mg / KgBB.Total flavonoid contained on kirinyuh leaves ethanol extract that is 16,786 mg/g.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Chromolaena odorata Linn, makanan tinggi purin, asam urat, hiperurisemia
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: Users 438 not found.
Date Deposited: 02 Aug 2019 03:07
Last Modified: 02 Aug 2019 03:07
URI: http://repository.unsri.ac.id/id/eprint/1764

Actions (login required)

View Item View Item