EFEKTIVITAS ANTIBAKTERI KITOSAN CANGKANG KEPITING BAKAU (SCYLLA SERRATA) TERHADAP STREPTOCOCCUS MUTANS

SILPARENSI, SHAFA AL-AFIFAH and Negara, Mellani Cindera and Merdekawati, Listia Eka (2025) EFEKTIVITAS ANTIBAKTERI KITOSAN CANGKANG KEPITING BAKAU (SCYLLA SERRATA) TERHADAP STREPTOCOCCUS MUTANS. Undergraduate thesis, Sriwijaya University.

Preview	Image RAMA_12201_04031382126083_cover.jpeg - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (60kB) | Preview
	Text RAMA_12201_04031382126083.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy
	Text RAMA_12201_04031382126083_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (4MB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB)
	Text RAMA_12201_04031382126083_0007108701_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (368kB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (258kB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (271kB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (223kB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (144kB) | Request a copy
	Text RAMA_12201_04031382126083_0007108701_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy

Abstract

Background: Streptococcus mutans is the primary bacterium responsible for dental caries. One potential natural antibacterial agent is chitosan, which is derived from the shells of mangrove crabs (Scylla serrata). Chitosan has the ability to inhibit bacterial growth and induce bacterial cell death. Objective: To determine the antibacterial effectiveness of chitosan from mangrove crab (Scylla serrata) shell against Streptococcus mutans bacteria. Methods: An in vitro laboratory experimental design with a post-test-only control group was used. The study tested the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and inhibition zone of chitosan at concentrations of 1%, 0.5%, 0.25%, and 0.125%, with 0.2% chlorhexidine as a positive control and distilled water as a negative control. Each treatment was repeated four times. The MIC was determined using the broth dilution method, MBC with the agar dilution method, and the inhibition zone with the disc diffusion method. Results: The MIC was achieved at a concentration of 0.5%, while the MBC was not achieved even at a concentration of 1%. Inhibition zones were formed at 1% concentration with an average diameter of 0.32 mm and at 0.5% concentration with 0.28 mm. Conclusion: Chitosan derived from mangrove crab shells demonstrated antibacterial activity against Streptococcus mutans. however, its effectiveness was relatively low and not comparable to the positive control.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	antibacterial, chitosan, mangrove crab, Streptococcus mutans
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Shafa Al-afifah Silparensi
Date Deposited:	14 Jul 2025 07:03
Last Modified:	14 Jul 2025 07:03
URI:	http://repository.unsri.ac.id/id/eprint/178198

Actions (login required)

View Item