HUBUNGAN KADAR ALBUMIN SERUM DENGAN PERSENTASE DAN LOKASI EDEMA PADA ANAK PENDERITA SINDROM NEFROTIK DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

MARDIYYAH, AINUN and Lestari, Hertanti Indah and Akbari, Atika (2018) HUBUNGAN KADAR ALBUMIN SERUM DENGAN PERSENTASE DAN LOKASI EDEMA PADA ANAK PENDERITA SINDROM NEFROTIK DI RSUP DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Edema is a main clinical symptom in children with nephrotic syndrome. Edema in nephrotic syndrome divide into local and anasarca edema which can be explained by the underfill theory where hypoalbuminemia is the key. So far the percentage of edema in nephrotic syndrome is count by estimacy, while the dry weight of nephrotic syndrome patients is required to count the corticosteroid dose needed. This study seeks to determine the association between serum albumin levels with the percentage and location of edema in children with nephrotic syndrome at RSUP Dr. Mohammad Hoesin Palembang 2016-2017. Methods: This is a analytic observational research with cross-sectional design using secondary data. The sampling method was using consecutive sampling to all of medical records of children with nephrotic syndrome at RSUP Dr. Mohammad Hoesin Palembang during January 2016 - December 2017. There were 95 nephrotic syndrome patients during this study period from which 46 sample met inclusion and exclusion criteria. Results: Subjects were consisted of 26 (56,5%) boys dan 20 (43,5%) girls, with the average age of 7 years and 2 months old. Most of the patients (69,6%) lived outside Palembang and not referred patients (93,5%). The most common nephrotic syndrome diagnosis is initial nephrotic syndrome (32,6%). The lowest average of serum albumin levels can be found in the age of 4-6 years old (1,55 g/dL) while the highest can be found in the age of 13-15 years old (2,06 g/dL). The highest average of edema percentage can be found in the age of 1-3 years old (17,38%) while the lowest can be found in the age of 16-17 years old (3,98%). Majority of the patients is having anasarca edema (56,5%). The spearman analysis shows a significant correlation (p=0,003) with moderate power (r=-0,424) between serum albumin levels and the percentage of edema. Mann-Whitney shows (p=0,048) an assosiation between serum albumin levels and the location of edema. Conclusion: There are a significant correlation between serum albumin levels and the percentage of edema and a significant assosiation between serum albumin levels and the location of edema.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Nephrotic Syndrome, Hypoalbuminemia, The Percentage of Edema, Local Edema, Anasarca Ede
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Mrs Sri Astuti
Date Deposited:	02 Aug 2019 03:31
Last Modified:	02 Aug 2019 04:34
URI:	http://repository.unsri.ac.id/id/eprint/1829

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