KORELASI KADAR APOLIPOPROTEIN B SERUM DENGAN DERAJAT STENOSIS ARTERI KORONER BERDASARKAN SKOR SYNTAX PADA PASIEN SINDROM KORONER KRONIK DI RSUP Dr. MOHAMMAD HOESIN PALEMBANG

CHALIK, M. NOVRAN and Sukandi, Erwin and Irfannudin, Irfannudin (2025) KORELASI KADAR APOLIPOPROTEIN B SERUM DENGAN DERAJAT STENOSIS ARTERI KORONER BERDASARKAN SKOR SYNTAX PADA PASIEN SINDROM KORONER KRONIK DI RSUP Dr. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Background Chronic coronary syndrome (CCS) is a chronic form of coronary artery disease (CAD) that is generally stable but can progress and destabilize over time, often remaining clinically silent. Serum apolipoprotein B levels and the SYNTAX score can potentially be used to assess the risk of underlying atherosclerosis in chronic coronary syndrome. Methods A cross-sectional study involved 34 patients with chronic coronary syndrome at Dr. Mohammad Hoesin General Hospital Palembang. The diagnosis of chronic coronary syndrome was established based on the guidelines of the European Society of Cardiology (ESC). Data were collected through medical history taking, physical examination, laboratory tests, coronary angiography, and calculation of the SYNTAX score. Statistical analysis was performed using SPSS version 22. Results Of the 34 patients, 85.3% were male, with a mean age of 61.29 ± 9.63 years. The main risk factors included age (p = 0.039), dyslipidemia (p = 0.019), fasting blood glucose (p = 0.047), and triglyceride levels (p = 0.025). Statistical analysis showed a significant positive correlation between serum apolipoprotein B levels and the degree of coronary artery stenosis based on the SYNTAX score (r = 0.376, p = 0.029) Conclusion Serum apolipoprotein B levels are significantly correlated with the SYNTAX score in patients with chronic coronary syndrome. This study supports the use of apolipoprotein B as a marker for cardiovascular risk assessment and for the early identification of patients at high risk of atherosclerosis. Keywords Chronic coronary syndrome, SYNTAX score, degree of arterial stenosis, atherosclerosis

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Sindrom koroner kronik, derajat stenosis arteri koroner, skor SYNTAX
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine
Divisions:	04-Faculty of Medicine > 11702-Internal Medicine (Sp
Depositing User:	Muhammad Novran Chalik
Date Deposited:	25 Aug 2025 07:26
Last Modified:	25 Aug 2025 07:26
URI:	http://repository.unsri.ac.id/id/eprint/183223

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