THE EFFECT OF WHEY PROTEIN SUPPLEMENTATION ON SERUM ALBUMIN LEVELS AND HANDGRIP STRENGTH IN PATIENTS AT THE GERIATRIC CLINIC OF DR. MOHAMMAD HOESIN HOSPITAL PALEMBANG

AFRIANDO, REDHO and Riviati, Nur and Bahar, Erial (2025) THE EFFECT OF WHEY PROTEIN SUPPLEMENTATION ON SERUM ALBUMIN LEVELS AND HANDGRIP STRENGTH IN PATIENTS AT THE GERIATRIC CLINIC OF DR. MOHAMMAD HOESIN HOSPITAL PALEMBANG. Other thesis, Sriwijaya University.

Preview	Image RAMA_11702_04042782125001_cover.png - Cover Image Available under License Creative Commons Public Domain Dedication. Download (350kB) | Preview
	Text RAMA_11702_04042782125001.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (4MB) | Request a copy
	Text RAMA_11702_04042782125001_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (9MB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB)
	Text RAMA_11702_04042782125001_8876210016_9990000239_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (971kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (453kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (614kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (155kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_06.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_07_ref.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (166kB) | Request a copy
	Text RAMA_11702_04042782125001_8876210016_9990000239_08_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy

Abstract

Background: Aging leads to a progressive decline in muscle mass and strength, which contributes to reduced physical function in older adults. Malnutrition, particularly protein deficiency, is a major factor accelerating this decline. Whey protein is a high-quality protein rich in essential amino acids, especially branched-chain amino acids (BCAAs), and has the potential to improve serum albumin levels and muscle strength in the elderly. This study aimed to evaluate the effect of whey protein powder supplementation on serum albumin levels and handgrip strength in geriatric patients. Methods: This was an experimental, open-label clinical trial involving patients aged >60 years who met the inclusion and exclusion criteria. The intervention group received whey protein supplementation for 30 days. Serum albumin levels and handgrip strength were measured before and after the intervention. Data were analyzed using bivariate and multivariate statistical tests. Results: Forty geriatric patients (mean age 70.07 ± 5.40 years; 72.5% female) participated, with 65% at risk of malnutrition despite an average BMI within the normal–obese range. All participants had normal cognitive and mental status, and 90% reported high physical activity levels. After whey protein supplementation, serum albumin increased slightly (4.24 ± 0.31 to 4.27 ± 0.29 g/dL; p = 0.001), while handgrip strength improved significantly (25.22 ± 6.64 to 26.42 ± 7.04 kg; p = 0.002), albumin were not influenced by demographic or clinical factors, whereas handgrip strength improvement was positively predicted by better nutritional status (p = 0.028) and negatively by higher baseline physical activity (p = 0.026). Conclusion: Whey protein powder supplementation had a positive impact on handgrip strength but only a minimal effect on serum albumin levels in older adults. This intervention may serve as a nutritional strategy to improve functional status in geriatric care. Keywords: elderly, whey protein, albumin, muscle strength, handgrip, malnutrition

Item Type:	Thesis (Other)
Uncontrolled Keywords:	whey protein, serum albumin, hand grip strength, geriatric patients, supplementation, elderly nutrition, clinical study
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine R Medicine > RC Internal medicine > RC620-627 Nutritional diseases. Deficiency diseases R Medicine > RC Internal medicine > RC925-935 Diseases of the musculoskeletal system R Medicine > RC Internal medicine > RC952-954.6 Geriatrics
Divisions:	04-Faculty of Medicine > 11702-Internal Medicine (Sp
Depositing User:	Redho Afriando
Date Deposited:	18 Sep 2025 01:29
Last Modified:	18 Sep 2025 01:29
URI:	http://repository.unsri.ac.id/id/eprint/183897

Actions (login required)

View Item