PERBANDINGAN EFEKTIVITAS MADU RANDU, GEL MADU RANDU, DAN GEL CARBOXYMETHYLCELLULOSE PADA LUKA SUPERFICIAL PARTIAL AKUT KERATOSIS SEBOROIK PASCA ELECTROSURGERY

RAHMADINI, MEIRINA and Aryani, Inda Astri and Yahya, Yulia Farida and Harahap, Debby Handayati (2025) PERBANDINGAN EFEKTIVITAS MADU RANDU, GEL MADU RANDU, DAN GEL CARBOXYMETHYLCELLULOSE PADA LUKA SUPERFICIAL PARTIAL AKUT KERATOSIS SEBOROIK PASCA ELECTROSURGERY. Undergraduate thesis, Sriwijaya University.

Preview	Image RAMA_11704_04082782125001_cover.jpg - Cover Image Available under License Creative Commons Public Domain Dedication. Download (408kB) | Preview
	Text RAMA_11704_04082782125001.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy
	Text RAMA_11704_04082782125001_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (439kB)
	Text RAMA_11704_04082782125001_8873130016_8806870018_002812830402_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (428kB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (25kB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (259kB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (224kB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (99kB) | Request a copy
	Text RAMA_11704_04082782125001_8873130016_8806870018_0028128304_07_Lam.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy

Abstract

Background: Seborrheic keratosis (SK) is a benign epithelial skin tumor, commonly found in the elderly. Electrosurgery for SK produces acute superficial partial-thickness wounds that require optimal wound care. Honey possesses antimicrobial, anti-inflammatory, and antioxidant properties that promote epithelialization. Randu honey is a widely available and affordable local honey in Indonesia, and it can be formulated into a gel. Carboxymethylcellulose (CMC) gel is a commonly used wound dressing. Objective: To compare the effectiveness of randu honey, randu honey gel, and CMC gel in the healing of acute superficial partial-thickness wounds following SK electrosurgery. Methods: A quasi-experimental pilot study was conducted at the Department of Dermatology, Venereology, and Aesthetics, Dr. Mohammad Hoesin General Hospital, Palembang, from May to August 2025. A total of 36 patients with SK who met the inclusion criteria were divided into three groups (randu honey, randu honey gel, and CMC gel). Effectiveness was assessed using a modified local skin reaction (LSR) scale, which included erythema, edema, crusting, and re-epithelialization. Pain was evaluated using the visual analog scale (VAS), and quality of life was measured with the dermatology quality of life index (DLQI). Data were analyzed using the sign test and Pearson’s Chi-square test. Results: Thirty-six patients participated, the majority of whom were female (58.3%), with a mean age of 53.72 years. Randu honey gel achieved the fastest erythema resolution (100%) by day 7. Edema and crusting resolved more quickly with randu honey gel and CMC gel (100%) by day 7. Complete re-epithelialization occurred earlier with randu honey gel and CMC gel (100%) by day 7. Pain reduction, based on VAS scores, was greatest with CMC gel (91.7%) by day 7. No significant differences in DLQI were observed among the three groups. No adverse effects were reported in any of the interventions. Conclusion: Randu honey and randu honey gel are effective wound dressings for acute superficial partial-thickness wounds after SK electrosurgery, with comparable outcomes to CMC gel. Keywords: Seborrheic keratosis, electrosurgery, wound dressing, randu honey, randu honey gel, carboxymethylcellulose

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Keratosis seboroik, electrosurgery, wound dressing, madu randu, gel madu randu,carboxymethylcellulose
Subjects:	R Medicine > RL Dermatology > RL1-803 Dermatology
Divisions:	04-Faculty of Medicine > 11704-Dermatology and Venereology (Sp
Depositing User:	Meirina Rahmadini
Date Deposited:	23 Sep 2025 07:06
Last Modified:	23 Sep 2025 07:06
URI:	http://repository.unsri.ac.id/id/eprint/184674

Actions (login required)

View Item