Hermansyah, Hermansyah (2010) Intracellular Ca2+ Regulation in Calcium Sensitive Phenotype of Saccharomyces cerevisiae. HAYATI Journal of Biosciences, 17 (1). pp. 123-127. ISSN 2086-4094
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Abstract
Intracellular cytosolic Ca2+ concentration accumulation plays an essential information in Saccharomyces cerevisiae i.e. to explain cellular mechanism of Ca2+ sensitive phenotype. Disruption both S. cerevisiae PPase PTP2 and MSG5 genes showed an inhibited growth in the presence of Ca2+. On the other hand, by using Luminocounter with apoaequorin system, a method based upon luminescent photoprotein aequorin, intracellular Ca2+ concentration was accumulated as a consequence of calcium sensitive phenotype of S. cerevisiae. This fact indicated that PPase Ptp2p and Msg5p were involved in intracellular Ca2+ transport in addition their already known pathways i.e Mitogen Activated Protein Kinase cell wall integrity pathway, high osmolarity glycerol (HOG) pathway, and pheromone response FUS3 pathway.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Saccharomyces cerevisiae, protein phosphatase, calcium sensitivity, calcium accumulation |
| Subjects: | Q Science > Q Science (General) > Q1-295 General Q Science > QD Chemistry > QD1-999 Chemistry |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1) |
| Depositing User: | backup admin |
| Date Deposited: | 09 Jan 2020 07:05 |
| Last Modified: | 09 Jan 2020 07:05 |
| URI: | http://repository.unsri.ac.id/id/eprint/23375 |
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