Secondary Metabolite from Endophytic Fungi Aspergillus Niger of The Stem Bark of Kandis Gajah (Garcinia Griffithii)

Elfita, Elfita and Muharni, Muharni and Munawar, Munawar and Aryani, Septa (2012) Secondary Metabolite from Endophytic Fungi Aspergillus Niger of The Stem Bark of Kandis Gajah (Garcinia Griffithii). Indonesian Journal of Chemistry, 12 (2). pp. 195-200. ISSN 1411-9420

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Abstract

Garcinia griffithii are known as kandis gajah including the Garcinia genus. This plant has been traditionally used by local communities Sarasah Bonta, Lembah Arau, West Sumatra, to treat various diseases including gout. Aspergillus niger was isolated from the tissues of the stem bark of Garcinia griffithii. The fungi strain was identified base on colony and cell morphology characteristic. Aspergillus niger cultured in media 5 L Potatos Dextose Broth (PDB) for 8 weeks and filtered. Media that already contains secondary metabolites are partitioned using ethyl acetate solvent in 5 L (twice), followed by evaporation. Furthermore, the extract is separated by chromatographic techniques to obtain a pure compound form of white crystal. The molecular structure of compound isolation result are determined by spectroscopic methods including IR, 1H-NMR, 13C-NMR, HMQC, HMBC, and COSY. The compound was determined as phenolic (1).

Item Type: Article
Subjects: Q Science > QD Chemistry > QD1-999 Chemistry
Divisions: 08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1)
Depositing User: Dr. Elfita, M.Si
Date Deposited: 16 Jan 2020 07:02
Last Modified: 16 Jan 2020 07:02
URI: http://repository.unsri.ac.id/id/eprint/24267

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