KARAKTERISTIK PATCH YANG DIINKORPORASI DENGAN MINYAK ATSIRI KEMANGI

SAFITRI, RIANI and Miksusanti, Miksusanti and Elfita, Elfita (2019) KARAKTERISTIK PATCH YANG DIINKORPORASI DENGAN MINYAK ATSIRI KEMANGI. Undergraduate thesis, Sriwijaya University.

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Abstract

Incorporation of basil essential oils into patch had been doneThe aim of this research to determine the effect of concentration variations of basil essential oils incorporated into HPMC (Hydroxy Propyl Methyl Cellulose) and chitosan polymer based patch. . Observation parameters were antibacterial activity patch against Streptococcus mutans and physical properties. Patch was made by solvent casting method with variations in the concentration of basil essential oil that were (0, 18, 36, 54, 72, dan 90) mg/mL. Antibacterial activity test was conducted using disc diffusion method. The results showed that each patch formula had variance of weight values 58,3-96,7 mg, thickness 0,11-0,23 mm, folding endurance >300 folds, also good swelling index. Patch contained basil essential oils with a concentration of 90 mg/mL was determined as MIC95 value because it could inhibited the growth of Streptococcus mutans by 95,22%. Antibacterial compounds detected in the GC-MS instrument were linalool and methylcavicol.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Minyak atsiri kemangi, Patch, Streptococcus mutans, HPMC dan kitosan.
Subjects:	Q Science > QD Chemistry > QD415-436 Biochemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1)
Depositing User:	Users 1075 not found.
Date Deposited:	07 Aug 2019 07:34
Last Modified:	07 Aug 2019 07:34
URI:	http://repository.unsri.ac.id/id/eprint/2741

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