PREPARASI DAN KARAKTERISASI NANOPARTIKEL EMAS EKSTRAK KUNYIT PUTIH (Curcuma zedoaria (Berg.) Roscoe) DENGAN VARIASI KONSENTRASI LARUTAN ASAM KLOROAURAT (HAuCl4)

PEBRIANI, ZELLA and Mardiyanto, Mardiyanto and Solihah, Indah (2020) PREPARASI DAN KARAKTERISASI NANOPARTIKEL EMAS EKSTRAK KUNYIT PUTIH (Curcuma zedoaria (Berg.) Roscoe) DENGAN VARIASI KONSENTRASI LARUTAN ASAM KLOROAURAT (HAuCl4). Undergraduate thesis, Sriwijaya University.

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Abstract

Gold nanoparticles have been successfully synthesized using the green synthesis method. Green synthesis method is a way of making nanoparticles by utilizing white turmeric (Curcuma zedoaria (Berg.) Roscoe) as a bioreductor to reduce Au3+ to Au0. White turmeric rhizome extract has a total phenolic of 64.1025 ± 1.234 mg/GAE. The components of gold nanoparticles consisted of extracts of 30 mg, and a solution of acid tetrachloroauric (HAuCl4) with concentrations variation of 0.25 mM, 1 mM, and 2 mM, and observed changes in the color of the solution, wavelength, %EE value, characterization of particle size, PDI, zeta potential, antioxidant activity, and stability test of gold nanoparticles extract of white turmeric. The results obtained from visual observations, wavelength observations on the UV-Vis spectrophotometer, formula II (1 mM) as the optimum concentration in the manufacture of gold nanoparticles with extracts of 30 mg as a bioreductor and stabilizing agent. The optimum formula has a wavelength of 535 nm, and has a %EE value is 90.44% ± 0.0923. The Optimum Formula has a particle size 55.2 nm; PDI value 0.341 and potential zeta -20.4 mV. IC50 values of quercetin, white turmeric rhizome extract, gold nanoparticles without extracts, and optimum formulas were respectively 12.310 μg / mL; 16,2685 μg / mL; 30,1682 μg / mL, and 25,2426 μg / mL which are included in the category of very strong antioxidants. Keywords: Gold nanoparticles, white turmeric (Curcuma zedoaria (Berg) Roscoe) extract, Green synthesis, Bioreductor, antioxidant.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Nanopartikel emas, ekstrak rimpang kunyit putih (Curcuma zedoaria (Berg) Roscoe), Green synthesis, Bioreduktor, antioksidan.
Subjects:	R Medicine > RS Pharmacy and materia medica > RS192-199 Pharmaceutical technology
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Users 5829 not found.
Date Deposited:	29 May 2020 07:09
Last Modified:	29 May 2020 07:09
URI:	http://repository.unsri.ac.id/id/eprint/29517

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