Fitrya, Fitrya (2016) ETHANOL EXTRACT FORMULATION OF TUNJUK LANGIT RHIZOME AS TABLET BY WET GRANULATION METHOD. Jurnal Farmasi GALENIKA, 3 (1). pp. 8-12. ISSN 2579-4469
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Abstract
Tunjuk langit rhizome (Helminthostahcys zeylanica (Linn) Hook) has been used traditionally as an anticancer and antiinflammatory agent. Previous studies have proved the potency of ethanol extract from this rhizome as an antihyperuricemic agent. In this study, the ethanol extract of the rhizome, was formulated into tablet dosage forms by a wet granulation method. Three tablet formulas with different types of disintegrant and binder were formula A (starch: PVA), formula B (Avicel®PH102: PVP), and formula C (sodium alginate: methylcellulose). Physical properties (such as weight variation, tablet diameter, thickness, friability, hardness, and disintegration time) and dissolution of tablets were evaluated. The analysis results showed that formula A produced the best physical properties and dissolution characteristics.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Tunjuk Langit Rhizome, Helminthostachys zaylanica, starch, polyvinil alcohol (PVA) |
| Subjects: | #3 Repository of Lecturer Academic Credit Systems (TPAK) > Hak Atas Kekayaan Intelektual (HAKI)-PATENT |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1) |
| Depositing User: | M.Si, Apt. Fitrya Fitrya |
| Date Deposited: | 28 Dec 2020 03:47 |
| Last Modified: | 28 Dec 2020 03:47 |
| URI: | http://repository.unsri.ac.id/id/eprint/39010 |
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