KARAKTERISTIK KEHAMILAN DENGAN LES (LUPUS ERITEMATOSUS SISTEMIK) DI RUMAH SAKIT DR. MOHAMMAD HOESIN PALEMBANG

MUTHMAINNAH, NYIMAS ALIYAH FAIZATUN and Nuswil, Bernolian and Eddy, Roflin (2020) KARAKTERISTIK KEHAMILAN DENGAN LES (LUPUS ERITEMATOSUS SISTEMIK) DI RUMAH SAKIT DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with complex pathogenesis with broad clinical manifestations, more common in women of reproductive age between 15-44 years, so there is an increased incidence of pregnancies. Methods: This study was a descriptive observational study with a cross-sectional design using medical records of patients in Dr. Mohammad Hoesin Hospital Palembang in the period January 2018-June 2020. Sampling was carried out by total sampling with the presentation of data in the form of tables and narratives. Results: There were 1,039 pregnancies in the period January 2018-June 2020 with 26 pregnancies with SLE with 8 patients (30.8%) of moderate degree SLE. The demographic characteristics of the patients were obtained by the patient's age in the age range of 26-30 years old (30.8%), high school education status (53.8%), the number of pregnancies 2-3 times (53.8%), the number of primiparous births (46.2 %), and the number of miscarriages was never experienced (65.4%). Characteristics of clinical signs and symptoms, namely malaise (15.4%), malar rash, photosensitivity spots and alopecia (15.4%), inflammatory arthritis (46.2%), lupus nephritis (11.5%), abdominal pain ( 34.6%), lymphadenopathy (3.8%), anemia or lymphopenia (15.4%), and cephalgia (7.7%). Meanwhile, the parameter of diagnosis was lymphopenia (15.4%), eGFR stage 1 (34.6%), proteinuria or proteinuria and cylinderuria (11.5%), ANA test (+) (19.2%), anti-dsDNA test (+) (19.2%), and the complement test decreased (7.7%). Pregnancy outcomes were found to have intrauterine growth restriction (IUGR) (19.2%) and preeclampsia and IUGR (11.5%). Conclusion: From the 26 pregnant patients with SLE, most were found with moderate degree. Most demographic characteristics were age range 26-30 years old, high school education status, number of pregnancies 2-3 times, primipara, and never miscarriage. Characteristics of clinical signs and symptoms, most commonly found in patients were malaise, malar rash, photosensitivity spots and alopecia, inflammatory arthritis, and abdominal pain. The parameters of diagnosis were lymphopenia, stage 1 eGFR, proteinuria or proteinuria and cylinderuria, ANA test (+), and anti-dsDNA test (+). Most pregnancy outcome is intrauterine growth restriction (IUGR).

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Lupus Eritematosus Sistemik (LES), Kehamilan, Kehamilan dengan Lupus Eritematosus Sistemik (LES), Lupus Eritematosus Sistemik pada kehamilan
Subjects:	R Medicine > RG Gynecology and obstetrics > RG551-591 Pregnancy
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Users 9687 not found.
Date Deposited:	11 Jan 2021 04:33
Last Modified:	18 Jun 2021 01:48
URI:	http://repository.unsri.ac.id/id/eprint/39623

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