MARVIKA, BERLIANA and Basir, Firmansyah and Martadiansyah, Abarham (2020) HUBUNGAN AWITAN PREEKLAMPSIA DENGAN LUARAN MATERNAL DAN PERINATAL DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE TAHUN 2019-2020. Undergraduate thesis, Sriwijaya University.
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Abstract
Background. Preeclampsia is defined as a syndrome that is unique to pregnancy, characterized by new-onset hypertension beginning ≥20 weeks of gestation and proteinuria. As a syndrome, it is also related to many organ systems. Based on the onset and the underlying pathophysiology, preeclampsia is classified into two subtypes: early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE). EO-PE is less prevalent but it is associated with increased risk of adverse maternal and perinatal outcomes to a greater degree than LO-PE. This study aimed to assess the relation between the onset of preeclampsia with maternal and perinatal outcomes at Dr. Mohammad Hoesin Central Hospital in Palembang. Methods. A cross sectional study was conducted among pregnant women with preeclampsia who gave birth at Dr. Mohammad Hoesin Central Hospital, a tertiary care facility in Palembang on July 2019-July 2020. The data was collected by using medical records. Total sampling was chosen as the sampling technique. Descriptive statistics, both univariate and bivariate, were performed first, then the data was analyzed by binary logistic regression to account for the relation between the onset of preeclampsia with maternal and perinatal outcomes. Results. Showed 212 preeclamptic mothers, 82 (38.7%) cases were early-onset preeclampsia (EO-PE) and the rest 130 (61.3%) cases were late-onset preeclampsia (LO-PE). The EO-PE group had higher risk of developing HELLP syndrome (OR=4.919, p-value 0.000), SGA (OR= 4.919, p-value 0.000), LBW (OR= 14.265, p-value 0.000), asphyxia (OR= 3.226, p-value 0.001), and perinatal death (OR= 19.147, p-value 0.000) compared to the LO-PE group. Meanwhile, the relation between the onset of preeclampsia with eclampsia (OR= 2.305, p-value 0.073), placental abruption (OR= 3.951, p-value 0.051), pulmonary edema (OR= 2.430, p-value 0.337), multiple organ failure (OR= 2.940, p-value 0.094), postpartum hemorrhage (OR= 0.309, p-value 0.287), and maternal death (OR= 0.790, p-value 0.848) didn’t reveal statistically significant. Conclusion. The study findings indicate that for some maternal and perinatal outcomes, women with EO-PE had a significantly higher risk for adverse outcomes than those with LO-PE. Keywords: Early-onset preeclampsia, EO-PE, Late-onset preeclampsia, EO-PE, Maternal Outcome, Perinatal Outcome
Item Type: | Thesis (Undergraduate) |
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Uncontrolled Keywords: | Preeklampsia awitan dini, preeklampsia awitan lanjut, luaran maternal, luaran perinatal |
Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) R Medicine > RG Gynecology and obstetrics > RG1-991 Gynecology and obstetrics R Medicine > RG Gynecology and obstetrics > RG500-991 Obstetrics |
Divisions: | 04-Faculty of Medicine > 11201-Medicine (S1) |
Depositing User: | Users 9627 not found. |
Date Deposited: | 11 Jan 2021 05:14 |
Last Modified: | 11 Jan 2021 05:14 |
URI: | http://repository.unsri.ac.id/id/eprint/39647 |
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