Electrospun Polyvinylpyrrolidone (PVP) Nanofiber Mats Loaded by Garcinia mangostana L. Extracts

Sriyanti, Ida and Edikresnha, Dhewa and Munir, Muhammad Miftahul and Rachmawati, Heni and Khairurrijal, Khairurrijal (2016) Electrospun Polyvinylpyrrolidone (PVP) Nanofiber Mats Loaded by Garcinia mangostana L. Extracts. Materials Science Forum, 880. pp. 11-14. ISSN 1662-9752

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Composite nanofibers of polyvinylpyrrolidone (PVP) and Garcinia mangostana L. extract (GME) have been synthesized through electrospinning method for application in drug delivery systems. The precursor solution of 10 mL PVP 10% w/w and GME 2% w/w was then electrospun collected at the rotating collector at the following optimum parameters: a voltage of 15 kV, a collector-nozzle distance of 12 cm, and a flow rate of 1 mL/hour. SEM images showed that the average diameters were 476 nm and 690 nm for the PVP and PVP-GME composite nanofibers, respectively. To some degree, the addition of GME into PVP nanofibers increased the average diameter size of nanofibers. Moreover, the release studies, it was shown that 80% of the GME was released within 30 minutes. Therefore, the PVP-GME composite nanofibers can be applied as the drug delivery systems.

Item Type: Article
Subjects: L Education > L Education (General) > L7-991 Education (General)
Q Science > QC Physics > QC1-999 Physics
Divisions: 06-Faculty of Education and Educational Science > 84103-Physics Education (S2)
Depositing User: Dr Ida Sriyanti, M.Si
Date Deposited: 01 Mar 2021 03:37
Last Modified: 01 Mar 2021 03:37
URI: http://repository.unsri.ac.id/id/eprint/39878

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