DAYA ANTIBAKTERI EKSTRAK DAGING IKAN PATIN (Pangasius sp.) TERHADAP BAKTERI Staphylococcus aureus

DHUHA, NEFIKA KIRANA and Dewi, Siti Rusdiana Puspa and Handayani, Pudji (2020) DAYA ANTIBAKTERI EKSTRAK DAGING IKAN PATIN (Pangasius sp.) TERHADAP BAKTERI Staphylococcus aureus. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that can be an opportunistic pathogen and has a fairly high level of resistance to antibiotics, therefore the development of new antibacterial compounds from natural ingredients is required. Catfish (Pangasius sp) are widely cultivated in South Sumatra, which has active substances in the form of fatty acids and amino acids that have antibacterial activity. Aim: To determine the antibacterial activity of catfish meat extract against S. aureus bacteria. Material and Methods: This study was an in vitro laboratory research with post-test only control group design in 7 treatment groups consisting of catfish meat extract with a concentration of 2.5%; 5%; 7,5%; 12,5%; 15%, distilled water as negative control and clindamycin as positive control. The extraction process of catfish meat extract meat used 96% ethanol solvent with maceration method. Antibacterial activity test of catfish meat extract against S. aureus was conducted using Kirby-bauer diffusion method to determine the zone of inhibition and minimum inhibitory concentration test using broth dilution method. Results: The results of this study showed that all concentrations of catfish meat extract had no antibacterial activity which shown by the absence of inhibition zones and cloudy appearance on test tube, while positive control had antibacterial activity. Conclusion: Based on the results of this study, it can be concluded that catfish meat extract had no antibacterial activity against bacteria S. aureus. Keywords: antibacterial, catfish, Pangasius sp, Staphylococcus aureus

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: antibakteri, ikan patin, Pangasius sp, Staphylococcus aureus.
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
Divisions: 04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User: Users 10496 not found.
Date Deposited: 28 Jan 2021 08:16
Last Modified: 28 Jan 2021 08:16
URI: http://repository.unsri.ac.id/id/eprint/41353

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