PENGARUH GEL EKSTRAK KULIT NANAS (Ananas comosus L merr) TERHADAP PENYEMBUHAN ULSER MUKOSA MULUT(Studi pada Tikus Galur Wistar)

BAY, INDAH PRATIWI and Handayani, Pudji and Chairani, Shanty (2021) PENGARUH GEL EKSTRAK KULIT NANAS (Ananas comosus L merr) TERHADAP PENYEMBUHAN ULSER MUKOSA MULUT(Studi pada Tikus Galur Wistar). Undergraduate thesis, Sriwijaya University.

	Text RAMA_12201_04031181621019.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (6MB) | Request a copy
	Text RAMA_12201_04031181621019_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (4MB) | Request a copy
Preview	Text RAMA_12201_04031181621019_0004118405_0002108002_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (2MB) | Preview
	Text RAMA_12201_04031181621019_0004118405_0002108_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (781kB) | Request a copy
	Text RAMA_12201_04031181621019_0004118405_0002108_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (448kB) | Request a copy
	Text RAMA_12201_04031181621019_0004118405_0002108002_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (442kB) | Request a copy
	Text RAMA_12201_04031181621019_0004118405_0002108002_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (326kB) | Request a copy
	Text RAMA_12201_04031181621019_0004118405_0002108002_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (345kB) | Request a copy
	Text RAMA_12201_04031181621019_0004118405_0002108_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (4MB) | Request a copy

Abstract

Background: Ulcers are the most common lesions found on the oral mucosa. One of the herbal medicines that can be used for ulcer therapy is pineapple peel, because it contains flavonoid, saponin, tannin, and bromelain which have been known could help the healing process. This study was to determine the effect of pineapple peel extract gel against the healing of oral mucosal ulcers in wistar strain rats. Methods: A true experimental study in vivo with a pretest-posttest with control group design was carried out on 30 wistar strain rats, that were divided into 3 groups consist of 20% pineapple peel ethanol extract gel, 0.2% chlorhexidine gel as positive control and placebo gel as negative control. The ulcers were induced at the lower lip labial mucosa of rats using heated ball burnisher. The topical agents were applied to the ulcers 3 times a day for 7 days. Diameter of ulcer was measured on day 0,3,5, and 7 using the probe UNC-15 (mm). Data were analyzed using SPSS with a significance value of p<0.05. Results: The results of this study showed that there was significant difference in ulcer diameter reduction after 3 days of treatment between 20% pineapple peel extract gel and placebo gel (p<0.05). There was no significant difference in ulcer diameter reduction after 3 days of treatment among other groups (p>0.05). Conclusion: Pineapple peel extract gel 20% could stimulate ulcer healing so it can be used as an alternative agents for ulcer treatment. Keywords: ulcer, pineapple peel, Ananas comosus L merr, Wistar strain rats.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Ulser, Kulit Nanas, Ananas comosus L merr, Tikus Galur Wistar.
Subjects:	R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Users 11410 not found.
Date Deposited:	31 Mar 2021 02:06
Last Modified:	31 Mar 2021 02:06
URI:	http://repository.unsri.ac.id/id/eprint/44292

Actions (login required)

View Item