UJI AKTIVITAS PENYEMBUHAN LUKA TERBUKA EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus integer (Thunb.)Merr) PADA TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY

SIMARMATA, METANOIA and Mardiyanto, Mardiyanto and Solihah, Indah (2021) UJI AKTIVITAS PENYEMBUHAN LUKA TERBUKA EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus integer (Thunb.)Merr) PADA TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY. Undergraduate thesis, Sriwijaya University.

	Text RAMA_48201_08061381621070.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy
	Text RAMA_48201_08061381621070_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (5MB) | Request a copy
Preview	Text RAMA_48201_08061381621070_0010037102_0008038802_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (648kB) | Preview
	Text RAMA_48201_08061381621070_0010037102_0008038802_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (217kB) | Request a copy
	Text RAMA_48201_08061381621070_0010037102_0008038802_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (132kB) | Request a copy
	Text RAMA_48201_08061381621070_0010037102_0008038802_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (224kB) | Request a copy
	Text RAMA_48201_08061381621070_0010037102_0008038802_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (9kB) | Request a copy
	Text RAMA_48201_08061381621070_0010037102_0008038802_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (156kB) | Request a copy
	Text RAMA_48201_08061381621070_0010037102_0008038802_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy

Abstract

Untreated open wound will potentially lead to chronic infection. Chempedak (Artocarpus integer (Thunb.)Merr) leaf contain flavonoid that can help the wound healing process as antiinflamation, antibacterial, and antioxidant. This research is aiming to find the effect of giving etanol from chempedak leaf extract towards open wound healing rate. The test animal that consist of 25 Sprague Dawley rats, divided into 5 groups which consist of negative control test, positive control test, control test K1, K2, and K3. The observed parameter is the area of wound, wound healing percentage, and healing time. Area of wound was analyzed using ANOVA test to observe the differences between certain days of the observation. Phytochemical test result shows that ethanol extract from chempedak leaf (Artocarpus integer (Thunb.)Merr) fulfills the requirements from Materia Medika Indonesia (1989) and Depkes RI (2008). The research result shows that ethanol extract from chempedak leaf (Artocarpus integer (Thunb.)Merr) with 300 mg/kgBB dossage is proven to accelerate the healing rate, which was shown in rats that achieved healing rate of 90,356% in 20 days, where there was no significant difference (p>0,05) between cempedak leaf extract at a dose of 300 mg / kgBB against the positive control (Tekasol®) and significantly different from the negative control. Also, there is significant difference (p <0,05) between negative control and all control groups (positive, K1, K2, dan K3) on day 20, This shows that positive control and treatment with dosage variation can accelerate the healing rate on open wound.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Daun Cempedak (Artocarpus integer (Thunb.)Merr), luas luka, persentase penyembuhan luka, lama penyembuhan luka
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM1-950 Therapeutics. Pharmacology
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Users 11506 not found.
Date Deposited:	13 Apr 2021 01:55
Last Modified:	13 Apr 2021 01:55
URI:	http://repository.unsri.ac.id/id/eprint/44549

Actions (login required)

View Item