EFEKTIVITAS EKSTRAK DAUN MIANA (Coleus scutellarioides L. Benth) TERHADAP PERTUMBUHAN BAKTERI Streptococcus sanguinis

SALIMAH, KHOMISAH and Yasmin, Ulfa and Wahyuni, Sri (2021) EFEKTIVITAS EKSTRAK DAUN MIANA (Coleus scutellarioides L. Benth) TERHADAP PERTUMBUHAN BAKTERI Streptococcus sanguinis. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Dental caries is an infectious disease caused by a progressive demineralization process in the hard tissue of the teeth. The factors involved in dental caries process are host, substrate, time, and cariogenic microorganisms on plaque. The bacteria play a role in the early stages of plaque formation is Streptococcus sanguinis. Miana leaf is a plant that was reported to have antibacterial effects because it contained compounds such as flavonoids, tannins, alkaloids, saponins. Objective: The aim of this study was to determine the effectiveness of miana leaf (Coleus scutellarioides L. Benth) extract against bacterial growth of Streptococcus sanguinis. Materials and Methods: The material used in this study is miana leaves. This study was an experimental laboratory in vitro with a post test only control group design. The treatment group used miana leaf extract with concentration 5%, 10%, 15%, 20% dan chlorhexidine 0,2% as a positive control. The inhibition zone test used the disc diffusion method and minimum inhibitory concentration (MIC) test and minimum bactericidal concentration (MBC) used the dillution method. Result: MIC couldn’t be determined because it was blocked by the color of the extract and the MBC obtained at concentration 10%. The average of inhibition zone produced by miana leaf extract against Streptococcus sanguinis growth at concentration of 5% was 3,25±0,22 mm, 10% was 5,54±0,18 mm, 15% was 8,21±0,29, and the concentration with the greatest inhibition was 20% at 10,54±0,18 mm. Conclusion: Miana leaf (Coleus scutellarioides L. Benth) extract has an antibacterial effect against bacterial growth of Streptococcus sanguinist strart from concentration of 5%. Keywords: antibacterial, miana leaves, Streptococcus sanguinis

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	antibacterial, miana leaves, Streptococcus sanguinis
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Khomisah Salimah
Date Deposited:	27 May 2021 06:13
Last Modified:	27 May 2021 06:13
URI:	http://repository.unsri.ac.id/id/eprint/46848

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