UJI AKTIVITAS ANTIOKSIDAN EKSTRAK N-HEKSANA DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR DIINDUKSI ALOKSAN

WINDIASTUTI, PRIMA and Miksusanti, Miksusanti and Solihah, Indah (2021) UJI AKTIVITAS ANTIOKSIDAN EKSTRAK N-HEKSANA DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR DIINDUKSI ALOKSAN. Undergraduate thesis, Sriwijaya University.

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Abstract

The aims of this study are to determine the antioxidant activity of purple sweet potato leaves in inhibiting lipid peroxidation of blood and pancreas in rats. The solvent used is n-hexane, which is non polar solvent. The test of antioxidant activity using TBARS method by measuring the levels of malondialdehyde (MDA) plasma and pancreas induced by alloxan 150 mg/kg BW. The test animals were grouped into 6 groups where the normal group was given na-cmc only, positive control was given vitamin E 7,903 mg/kg BW, and for the treatment group was given a dose of n-hexane extract of purple sweet potato leaves 50, 100 and 200 mg/kg BW. The test results of the TBARS method indicate that at a dose of 200 mg/kg BW can reduce MDA plasma level 2,087 ± 0,067a and pancreatic MDA level 2,111 ± 0,083b. Statistic analysis of Duncan show that there is no significant different between the dose of 200 mg/kg BW and control positive group, so at dose 200 mg/kg BW has almost the same antioxidant activity as vitamin E.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	TBARS, aktivitas antioksidan, n-heksana, daun ubi jalar ungu.
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Prima Windiastuti
Date Deposited:	17 Jun 2021 06:43
Last Modified:	17 Jun 2021 06:43
URI:	http://repository.unsri.ac.id/id/eprint/48035

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