STANDARDISASI DAN FORMULASI SEDIAAN KRIM TABIR SURYA EKSTRAK ETANOL DAUN ALPUKAT (Persea americana) SERTA PENENTUAN NILAI SPF SECARA IN-VITRO

DIARTY, INTAN HELEN and Fitrya, Fitrya and Fithri, Najma Annuria (2018) STANDARDISASI DAN FORMULASI SEDIAAN KRIM TABIR SURYA EKSTRAK ETANOL DAUN ALPUKAT (Persea americana) SERTA PENENTUAN NILAI SPF SECARA IN-VITRO. Undergraduate thesis, Sriwijaya University.

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Abstract

Persea americana (avocado leaves) is a family of Lauraceae. Analysis with thin layer chromatography test showed positive reactions to flavonoid compounds. This compounds has potential as antioxidants source that can prevent the spread free radicals. This study aims to determine the antioxidants effect on avocado leaves ethanol extract concentration variation as an active ingredients in sunscreen cream and to know sun protection factor (SPF) value. Variation of extract concentration were given 5, 7.5, and 10 g in 50 g cream. Physical quality evaluation of cream consists of organoleptic, homogenity, adhesion ability, dispersion ability, protection ability, pH, and viscosity test. The result shows that avocado leaves extract cream comply with some parameters but doesn’t comply with viscosity test. The cream and avocado leaves extract SPF value were conducted by in-vitro using UV-Vis spectrophotometers. Determination of SPF values indicates the cream and avocado leaves ethanol extract has lower SPF value than cream in the market. Avocado leaves ethanol extract had SPF value 11.410 while the cream with concentration 5, 7.5, and 10 % had SPF value of 1.038, 1.130, and 1.359. Increasing value of SPF from avocado leaves ethanol extract cream was in accordance to the increase of extract concentration but it doesn’t comply as the best sunscreen.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Persea americana, cream, sun protection factor, sunscreen
Subjects: R Medicine > RS Pharmacy and materia medica > RS125-131.9 Formularies. Collected prescriptions
R Medicine > RS Pharmacy and materia medica > RS400-431 Pharmaceutical chemistry
Divisions: 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: Mrs Dies Meirita Sari
Date Deposited: 23 Aug 2019 08:17
Last Modified: 23 Aug 2019 08:17
URI: http://repository.unsri.ac.id/id/eprint/4835

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