APLIKASI DESAIN FAKTORIAL OPTIMASI EKSTRAKSI KULIT BATANG Vernonia amygdalina Del. DAN UJI ANTIOKSIDAN KONSENTRASI OPTIMUM DENGAN METODE FRAP

SARI, BUNGA MONICA and Herlina, Herlina and Solihah, Indah (2018) APLIKASI DESAIN FAKTORIAL OPTIMASI EKSTRAKSI KULIT BATANG Vernonia amygdalina Del. DAN UJI ANTIOKSIDAN KONSENTRASI OPTIMUM DENGAN METODE FRAP. Undergraduate thesis, Sriwijaya University.

Preview	Text RAMA_48201_08121006063_0003077102_0008038802_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (774kB) | Preview
	Text RAMA_48201_08121006063_0003077102_0008038802_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (528kB) | Request a copy
	Text RAMA_48201_08121006063_0003077102_0008038802_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (404kB) | Request a copy
	Text RAMA_48201_08121006063_0003077102_0008038802_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (592kB) | Request a copy
	Text RAMA_48201_08121006063_0003077102_0008038802_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (10kB) | Request a copy
	Text RAMA_48201_08121006063_0003077102_0008038802_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (117kB) | Request a copy
	Text RAMA_48201_08121006063_0003077102_0008038802_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (959kB) | Request a copy

Abstract

Antioxidant are compounds who can resist free radical formation in the body. Free radical are reactive molecule can cause death cells. Natural compounds that are able to act as antioxidants are alkaloid, flavonoids, and phenol. One of the plants that are rich in this compounds is Vernonia amygdalina Del.This research is to optimize yield of rendement and total alkaloid content from stem skin african leaves (Vernonia amygdalina Del.) by investigating the effect of ethanol concentrations (50, 70, and 96% v/v) and stirring time (30, 60, and 90 min) on alkaloid extraction using factorial experiments. The difference in stirring time and solvent concentration with different polarity affects the acquisition of total alkaloid and the yield. The total number of alkaloids and the highest yield value become reference as an optimal treatment. Based on analysis design expert, the optimal treatment result in extraction with 96% ethanol solvent concentration and stirring time in 90 minutes. This result than performed an antioxidant test with FRAP (ferric reducing ability of plasma) method to measure the antioxidant capacity of the stem skin african leaves extract. The optimal treatment of stem skin african leaves extract obtained alkaloid total amount 18,572 mg AE/g and yield value amount 22,957%. That also shows the antioxidant power of 208,652 μg/mL.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Vernonia amygdalina Del., factorial design, stirring time, solvent concertration, ferric reducing ability of plasma (FRAP) method
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) R Medicine > RS Pharmacy and materia medica > RS192-199 Pharmaceutical technology
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Mrs Dies Meirita Sari
Date Deposited:	27 Aug 2019 05:31
Last Modified:	27 Aug 2019 05:31
URI:	http://repository.unsri.ac.id/id/eprint/4884

Actions (login required)

View Item