Harianja, sri hartati and Salni, Salni Peer review, Cytotoxic,Antiproliferation,and Necrosis Effects of then-Fraction Extract of Gendola Leaf( Basella rubra Linn.). Universitas diponegoro.
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Abstract
Breast cancer is the second most common cancer in women. Several studies have been conducted on natural materials to see the ability of its activity as a new anticancer compound. The purpose of this study was to determine the cytotoxic activity of Gendola leaf (Basella rubra Linn.) extracts and fractions,in inhibiting proliferation and inducing apoptosis of T 47 Hexane D breast cancer cells. The design of this study was experimental laboratory research using the in vitro method. Cytotoxic and anti- proliferation tests on T 47 D cancer were using the MTT method, and the apoptosis test was using the flow cytometry method. Cytotoxic of extracts and fractions of n-hexane Gendola leaves were tested with a concentration series of 1000 ; pg /mL and doxorubicin was studied a series concentration of 0.03125 pg/mLfor 24 concentration series of 1 IC and 1n IC 50 48 0.5;500 0.25;; 250;0.125 hours.Antiproliferation test used nhexane fraction with a 50,V2 IC 50,V4 IC50,and V8 IC50 125;with an incubation time of hours
| Item Type: | Other |
|---|---|
| Subjects: | |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1) |
| Depositing User: | Salni Salni |
| Date Deposited: | 28 Sep 2021 10:00 |
| Last Modified: | 28 Sep 2021 10:00 |
| URI: | http://repository.unsri.ac.id/id/eprint/50375 |
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