SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL Spirulina platensis TERHADAP BAKTERI Methicillin Resistant Staphylococcus aureus (MRSA) DAN Vancomycin Resistant Enterococci (VRE)

SAPUTRA, HANIP RIDHO and Untari, Budi and Mulyani, Laida Neti (2018) SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL Spirulina platensis TERHADAP BAKTERI Methicillin Resistant Staphylococcus aureus (MRSA) DAN Vancomycin Resistant Enterococci (VRE). Undergraduate thesis, Sriwijaya University.

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Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococci (VRE) are the most common pathogenic bacterias resulting in nosocomial infections in hospitals and have been resistant to antibiotics. Spirulina platensis is a microalgae belonging to the blue-green algae group (Cyanophyta), containing bioactive substance that can be used as anti-bacterial agent. To obtain bioactive substances on Spirulina platensis as an antibacterial agent was done by maceration and sonication extraction. The aim of this research was to find out the class of secondary metabolite compounds which was contained in Spirulina platensis ethanol extract and to know its antibacterial ability against MRSA and VRE bacteria. The results of phytochemical screening of ethanol extract Spirulina platensis contain flavonoid, saponin, phenolic, and steroidal compounds. TLC analysis showed that ethanol extract Spirulina platensis contains flavonoid group compounds. Spirulina platensis ethanol extract gave inhibitory activity against MRSA and VRE with MIC 8 and 4% respectively with mean value of inhibit zone diameter 0.62 ± 0.11 and 0.68 ± 0.23 mm.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Spirulina platensis, Methicillin-Resistant Staphylococcus aureus, Vancomycin Resistant Enterococci, antibacteria
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS400-431 Pharmaceutical chemistry
Divisions: Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: Mrs Dies Meirita Sari
Date Deposited: 24 Jul 2019 01:48
Last Modified: 24 Jul 2019 01:48
URI: http://repository.unsri.ac.id/id/eprint/624

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