OPTIMASI PROSES EKSTRAKSI BUNGA TELANG (Clitoria ternatea) MENGGUNAKAN ULTRASONIC-ASSISTED EXTRACTION DENGAN PARAMETER KADAR ANTOSIANIN DAN AKTIVITAS ANTIOKSIDAN

AULIANISA, FIRIYALIZA and Shiyan, Shaum and Agustiarini, Vitri (2022) OPTIMASI PROSES EKSTRAKSI BUNGA TELANG (Clitoria ternatea) MENGGUNAKAN ULTRASONIC-ASSISTED EXTRACTION DENGAN PARAMETER KADAR ANTOSIANIN DAN AKTIVITAS ANTIOKSIDAN. Undergraduate thesis, Sriwijaya University.

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Abstract

Butterfly pea flower (Clitoria ternatea) contains anthocyanins which are pigments from flavonoids which are antioxidants. The purpose of this study was to determine the best ultrasonic extraction temperature, time, and concentration based on the determination of the percent yield, anthocyanin content, and IC₅₀ antioxidant activity. The research was conducted by varying the temperature (25℃, 42.5℃, 60℃), time (10, 20, 30 minutes), and ethanol concentration (40%, 60%, 80%). Determining the best extraction conditions was carried out using the CCD (Central Composite Design). The results showed that the optimum extraction conditions were obtained at extraction temperature of 47℃, extraction time of 30 minutes, and 50% ethanol concentration resulting in a yield of 24.9%, anthocyanin content of 395,430 mg/100g, and antioxidant activity of 33,475 g/mL. The selected optimum response can meet the wishes according to the criteria with the desired value of 86.8%. Based on the characterization test of the extract under optimum conditions which included moisture content, drying shrinkage, and total ash content, the results were obtained that met the requirements of the Indonesian Herbal Pharmacopoeia. Butterfly pea flower (Clitoria ternatea) contains anthocyanins which are pigments from flavonoids which are antioxidants. The purpose of this study was to determine the best ultrasonic extraction temperature, time, and concentration based on the determination of the percent yield, anthocyanin content, and IC₅₀ antioxidant activity. The research was conducted by varying the temperature (25℃, 42.5℃, 60℃), time (10, 20, 30 minutes), and ethanol concentration (40%, 60%, 80%). Determining the best extraction conditions was carried out using the CCD (Central Composite Design). The results showed that the optimum extraction conditions were obtained at extraction temperature of 47℃, extraction time of 30 minutes, and 50% ethanol concentration resulting in a yield of 24.9%, anthocyanin content of 395,430 mg/100g, and antioxidant activity of 33,475 g/mL. The selected optimum response can meet the wishes according to the criteria with the desired value of 86.8%. Based on the characterization test of the extract under optimum conditions which included moisture content, drying shrinkage, and total ash content, the results were obtained that met the requirements of the Indonesian Herbal Pharmacopoeia.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Antosianin, Central Composite Design, Clitoria ternatea, Ultrasonic Assisted-Extraction, IC₅₀ antioksidan
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Firiyaliza Aulianisa
Date Deposited:	12 Aug 2022 04:53
Last Modified:	12 Aug 2022 04:53
URI:	http://repository.unsri.ac.id/id/eprint/77166

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