Antioxidant and Antimicrobial Activity of Endophytyc Fungi Isolated from Syzygium aqueum Leaves

Habisukan, Ummi Hiras and Elfita, Elfita and Widjajanti, Hary and Setiawan, Arum and Kurniawati, Alfia R (2021) Antioxidant and Antimicrobial Activity of Endophytyc Fungi Isolated from Syzygium aqueum Leaves. Journal of Physics: Conference Series, 1751. pp. 1-8. ISSN 17426596

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Abstract

Syzygium aqueum is a widely used medicinal plant species with ethnomedicinal values. Despite the plant, the endophytes are recognized as a rich source of secondary metabolites with potentially useful pharmacological properties. This study was aimed to identify the endophytic fungi from S.aqueum leaves and discover their antioxidant and antimicrobial activity. The ethyl acetate extracts of the isolated endophytic fungi were investigated for their antioxidant and antimicrobial activity using 1,1diphenyl-2-picryl hydrazyl (DPPH) method and paper disc diffusion assay, respectively. The antimicrobial activity was evaluated against three pathogen bacteria : Staphylococcus aureus, Salmonella thypi, and Escherichia coli, and one yeast: Candida albicans. Three endophytic fungi were obtained from S. aqueum leaves. Based on morphological characteristics, those fungi identified as Cochliobolus sp (D22), Penicillium sp. (D32), and Fusarium sp. (D41). Penicillium sp. (code D32) showed significant antioxidant potential activity as an also significant antimicrobial activity with IC50 59,16% and highest zone inhibition against E. coli 13.38 ± 0.25 mm. It is worth considering a further investigation of their bioactive secondary metabolites and isolates the bioactive compound for the antioxidant and antimicrobial agents.

Item Type: Article
Additional Information: Prosiding dipublikasi dan disajikan ber ISSN atau ISBN (Internasional terindeks pada ScimagoJr dan Scopus)
Subjects: Q Science > QP Physiology > QP(901)-(981) Experimental pharmacology
Divisions: 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1)
Depositing User: Dr Arum Setiawan
Date Deposited: 14 Dec 2022 05:38
Last Modified: 14 Dec 2022 05:38
URI: http://repository.unsri.ac.id/id/eprint/83678

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