RASIONALITAS PENGGUNAAN ANTIDIABETIK ORAL PADA PENDERITA DIABETES MELITUS TIPE 2 DI RUMAH SAKIT MUHAMMADIYAH PALEMBANG PERIODE JULI 2010-AGUSTUS 2011

YUSMARITA, IKA PUTRI and Aziz, Syahril and Theodorus, Theodorus (2012) RASIONALITAS PENGGUNAAN ANTIDIABETIK ORAL PADA PENDERITA DIABETES MELITUS TIPE 2 DI RUMAH SAKIT MUHAMMADIYAH PALEMBANG PERIODE JULI 2010-AGUSTUS 2011. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Recently, Irrational use of drugs has been a global problem. WHO estimates that more than 50% of therapy is irrational use of drugs and half of patients fail to consume drug properly (giving or excessive financing). So it can affect the quality of drug therapy, increase cost of therapy, the risk of unwanted effects, and influence psychological on society. The aim of this research was to determine the rationality of oral antidiabetic drugs use in patient with diabetes mellitus type 2 at Muhammadiyah Hospital. Methods: The drug utilization study have been conducted at Muhammadiyah Hospital from November until December 2011. The population and samples were obtained from medical record of patient with type 2 diabetes mellitus who used oral antidiabetic drugs from July 2010 until Agustus 2011. The variables were the pattern of drugs use, dose, frequency, route of administration, time of administration, duration of administration, contraindications, interactions with another drugs, the follow up, generic or brand name of drugs, and the efficacy. Results: Most patients received glimepiride 2 mg in once a day in combination. The drugs which were the most often combined with oral antidiabetic drugs were NSAIDs. Precise dose and frequency of administration were in 100% dan 76% samples. Adverse effects existed in 39,86% samples. There is contraindication, hepatitic, on two sample. The follow up, replacement and add drugs which have the rational dose and frequency of administration,was 48% samples. Generic (generic and brand) oral antidiabetic drugs were 64% samples. The efficacy exist on 62% samples. Conclusion: The number of sample which had the rational use of Antidiabetic oral (ADO) is only 38%. Therefore, the doctor and paramedic team in Muhammadiyah Palembang hospital need to increase the effort of the rational treatment on diabetic patient by using Antidiabetic oral (ADO).

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: the drug utilization, oral antidiabetic drugs, diabetes mellitus type 2
Subjects: R Medicine > RC Internal medicine > RC627.5-632 Metabolic diseases
Divisions: 04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User: Mrs Furika Furika
Date Deposited: 14 Dec 2022 07:53
Last Modified: 14 Dec 2022 07:53
URI: http://repository.unsri.ac.id/id/eprint/83746

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