KORELASI EKSPRESI CYCLOOXYGENASE-2 DENGAN SUBTIPE KARSINOMA NASOFARING

DEWI, NOVITA and Unita, Mezfi and Fantoni, Jusuf and Saleh, Irsan (2011) KORELASI EKSPRESI CYCLOOXYGENASE-2 DENGAN SUBTIPE KARSINOMA NASOFARING. Other thesis, Sriwijaya University.

	Text RAMA_11718_04072006001.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (27MB) | Request a copy
Preview	Text RAMA_11718_04072006001_9900982913_0029096608_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (10MB) | Preview
	Text RAMA_11718_04072006001_9900982913_0029096608_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (6MB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (524kB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (752kB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_06.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_07.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (628kB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_08_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (1MB) | Request a copy
	Text RAMA_11718_04072006001_9900982913_0029096608_09_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy

Abstract

Background Nasopharyngeal carcinoma (NPC) is a malignant tumor that tends to be diagnosed at cm advanced stage, so they have low survival rate and poor prognosis. Cyclooxygenase-2 is an enzyme that is induced during injlammation and neoplastic and expressed in various tumors. The aim of this study is to evaluate the expression of cyclooxygenase-2 in nasopharyngeal carcinoma and to assess the correlation of expression of cyclooxygenase-2 with nasopharyngeal carcinoma subtype Material and Method. This research an observasional correlative analysis study in the form of serial cases with 30 samples of nasopharyngeal carcinoma preparations consisted of 21 cases of non keratinizing undifferentiated nasopharyngeal carcinoma and 9 cases of non keratinizing differentiated nasopharyngeal carcinoma at Anatomic Pathology of Dr. Mohammad Hoesin General Hospital in Palembang on June 2010-June 2011. Cyclooxygenase-2 immunohistochemical stains were performed and the correlation between expression of cyclooxygenase-2 were assesses and analyzed by non-parametric Spearman correlation test. Result Thirty cases of nasopharyngeal carcinoma obtained positifity cyclooxygenase-2 is 63.3% and positifity bot h subtypes of nasopharyngeal carcinoma w as 43.3% are non keratinizing undifferentiated nasopharyngeal carcinoma and 20% is differentiated. Spearman correlation test showed significant correlation between expression of cycIooxygenase-2 and subtypes of nasopharyngeal carcinoma (p> 0.05). Conclusion. In this study we can conclude that there was no significant correlation between expression of cyclooxygenase-2 and subtypes of nasopharyngeal carcinoma

Item Type:	Thesis (Other)
Uncontrolled Keywords:	correlation, nasopharyngeal carcinoma, cyclooxygenase-2
Subjects:	R Medicine > RF Otorhinolaryngology > RF341-437 Rhinology. Diseases of the nose, accessory sinuses, and nasopharynx
Divisions:	04-Faculty of Medicine > 11718-Pathology Anatomy (Sp
Depositing User:	Mrs Furika Furika
Date Deposited:	31 Jan 2023 07:07
Last Modified:	31 Jan 2023 07:07
URI:	http://repository.unsri.ac.id/id/eprint/88789

Actions (login required)

View Item