LEO, ANDRI CORENTUS and Sinulingga, Sadakata and Sulistiawati, Sulistiawati (2013) UJI DAYA HAMBAT EKSTRAK KAKAO (Theobroma cacao) TERHADAP JAMUR Candida albicans PENYEBAB DENTURE STOMATITIS. Undergraduate thesis, Sriwijaya University.
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Abstract
Background: Denture stomatitis is a chronic infection that caused by Candida albicans that occurs in 15% to 65% people who wear full or partial denture. The aim ofthis research was to evaluate the effect of extract cacao (Theobroma cacao) seed in inhibiting the growth of C.albicans. Method: This research was conducted by using multilevel maceration techniques with n-hexane, ethyl acetate, and ethanol solvents to determine whether cacao seed extract can inhibit the growth of C.albicans causing denture stomatitis. An experimental study had been done in Chemistry Laboratory FMIPA UNSRI and BBLK Palembang on September 2012. The inhibition test ofC.albicans was done by counting the amount ofC.albicans colonies that grew in Sabouraud’s Dextrose Agar (SDA) media measured in Colony Forming Unit per mili-litre (CFU/ml). The result was analyzed with Analysis of Variance (ANOVA) and continued with post hoc LSD. Result: The most effective solvent which could extract out antifungal compounds ffom cacao seed was ethanol. Cacao seed ethanol extract of 15%, 20%, 25%, 30%, and 35% consentration can inhibit the growth of C.albicans significantly compared with the negative control group (p<0,05). Conclusion: Ethanol extract of cacao seed can inhibit the growth ofC.albicans. Keyword: Extract, Cacao seed, C.albicans, Denture Stomatitis.
Item Type: | Thesis (Undergraduate) |
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Uncontrolled Keywords: | Extract, Cacao seed, C.albicans, Denture Stomatitis |
Subjects: | R Medicine > RL Dermatology > RL201-331 Hyperemias, inflammations, and infections of the skin |
Divisions: | 04-Faculty of Medicine > 11201-Medicine (S1) |
Depositing User: | Mrs Beta Ria Febrianti |
Date Deposited: | 17 Feb 2023 05:16 |
Last Modified: | 17 Feb 2023 05:29 |
URI: | http://repository.unsri.ac.id/id/eprint/89665 |
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