Arrahmanda, K. and Ahmad, Z. and Sudarto, Sudarto and Rasyid, A. and Yuwono, Yuwono (2011) EFFECT OF EXON 1 CODON 52 AND 54 MANNOSE BINDING LECTIN GENE POLYMORPHISM ON THE INCIDENCE OF PULMONARY TUBERCULOSIS. In: 16th Congress of the Asian Pacific Society of Respirology, 03 - 06 November 2011, Shanghai International Convention Center, Shanghai China.
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Abstract
Tuberculosis (TB) still world?s and Indonesia problem. Approximately one third of the world population ever infected with Mycobacterium tuberculosis (Mtb), but only about 10% become pulmonary TB. Presumably there is influence of individual genetic factors to TB infection. Mannose binding lectin (MBL) is an acute phase protein in a non specific immune system response which will bind Mtb and activate complement system to destroy the pathogen. Polymorphisms in exon 1 codon 52 and 54 might have correlation with decreasing of MBL protein in plasma and influence to opsonin function
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) |
| Divisions: | 04-Faculty of Medicine > 11201-Medicine (S1) |
| Depositing User: | Yon Yuwono |
| Date Deposited: | 18 Oct 2019 04:39 |
| Last Modified: | 18 Oct 2019 04:39 |
| URI: | http://repository.unsri.ac.id/id/eprint/11137 |
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