EFFECT OF D543N AND TGTG DELETION 3? UTR Nramp1 GENE POLYMORPHISMS AGAINST PULMONARY TUBERCULOSIS AT MELAYU ETHNIC OF SOUTH SUMATERA

Yuwono, Yuwono (2010) EFFECT OF D543N AND TGTG DELETION 3? UTR Nramp1 GENE POLYMORPHISMS AGAINST PULMONARY TUBERCULOSIS AT MELAYU ETHNIC OF SOUTH SUMATERA. In: International Eijkman Institute and NEHCRI Joint Symphosium, 13 - 15 Desember 2010, Hotel Borobudur Jakarta.

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Abstract

Pulmonary tuberculosis is still a major health problem with incidence on the world each year 139/100000 population and caused 1,8 million people death.Immunological finding showed that only 10% of population infected by Mycobacterium tuberculosis will get pulmonary tuberculosis, 90% were not get the disease. It is indicated that genetic factors controlling immune responses have major role in the pathogenesis of tuberculosis. Some studies showed 3 kind of genes have major contribution: Mbl gene encoding surface protein in attachment process. Nramp1 gene encoding protein in phogolysosome, responsible for phagocytosis process and Vdr gene encoding protein that regulate cellular immunity.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions: 04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User: Yon Yuwono
Date Deposited: 18 Oct 2019 04:45
Last Modified: 18 Oct 2019 04:45
URI: http://repository.unsri.ac.id/id/eprint/11142

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