POLA KUMAN DAN KEPEKAAN ANTIBIOTIK BERDASARKAN HASIL PEMERIKSAAN KULTUR SEKRET LUKA KAKI DIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI RAWAT INAP RSUP DR. MOHAMMAD HOESIN PERIODE JANUARI 2021—DESEMBER 2022

HASIBUAN, AHMAD FAUZI and Anggraini, Ratna Maila Dewi and Kurniati, Ardesy Melizah (2023) POLA KUMAN DAN KEPEKAAN ANTIBIOTIK BERDASARKAN HASIL PEMERIKSAAN KULTUR SEKRET LUKA KAKI DIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI RAWAT INAP RSUP DR. MOHAMMAD HOESIN PERIODE JANUARI 2021—DESEMBER 2022. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: The causative germ of diabetic foot infections are highly diverse and are usually treated with antibiotics. Inappropriate use of antibiotics can influence germs to become resistant and result in increased severity and mortality. Study on the distribution of germs and their sensitivity is rarely conducted in Palembang. Some studies only identify 1 type of germ so it does not describe the overall distribution. The purpose of this study was to identify germ and antibiotic susceptibility patterns in DM type 2 patiens with diabetic foot ulcers at the Inpatient Installation of RSUP Dr. Mohammad Hoesin Palembang. Methods: This study was descriptive observational with total sampling. The data used were medical record and resistance culture laboratory results with specimen post-debridement secretion swabs of diabetic foot ulcer in type 2 diabetes mellitus patients who underwent hospitalization in the period January 2021–December 2022. Results: There were 102 germ isolates obtained from resistance cultures of 76 samples. Gram-negative strains were the most common type of germ (86.3%) which placed Acinetobacter baumannii (19.6%) as the highest germ. Gram-positive germs (13.7%) were dominated by Staphylococcus spp (12.7%). Acinetobacter baumannii was sensitive to tigecycline (90%) and were resistant to ampicillin (94.1%), ceftriaxone (94.1%), and cefazolin (94.1%). Staphylococcus spp were sensitive to linezolid (100%), nitrofurantoin (100%), quinupristin/dalfopristin (100%), rifampicin (100%), tigecycline (100%) and resistant to benzylpenicillin (100%). Conclusion: Almost all Gram-negative isolates were sensitive to aminoglycoside antibiotics (amikacin) and resistant to cefazolin. Gram-positive isolates were sensitive to linezolid, nitrofurantoin, quinupristin/dalfopristin, tigecycline and entirely resistance to benzylpenicillin. Keywords: Diabetic foot ulcer, germ pattern, antibiotic susceptibility, post debridement secretion swab.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Luka kaki diabetik, pola kuman, kepekaan antibiotik, swab sekret pascadebridemen
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Ahmad Fauzi Hasibuan
Date Deposited:	21 Dec 2023 01:58
Last Modified:	21 Dec 2023 01:58
URI:	http://repository.unsri.ac.id/id/eprint/136604

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