UJI DAYA HAMBAT EKSTRAK DAUN SIRSAK (Annona muricata L.) TERHADAP PERTUMBUHAN BAKTERI Streptococcus sanguinis

NURAZIMAH, R.A.MUTHIAH and K, Trisnawaty and Handayani, Pudji (2020) UJI DAYA HAMBAT EKSTRAK DAUN SIRSAK (Annona muricata L.) TERHADAP PERTUMBUHAN BAKTERI Streptococcus sanguinis. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Streptococcus sanguinis is the first bacterium to colonize tooth surfaces and a pioneer by forming dental plaque, which caused dental caries and periodontal disease. Soursop leaf have been reported to contain steroids, alkaloids, saponins, tannins, and flavonoids which have antibacterial potential. Aim: The purpose of this study was to investigate the antibacterial activity of soursop leaf extract against S. sanguinis bacteria growth. Method: The present study was an in vitro experimental laboratory research with post-test only control group design. This study used soursop leaf extract with concentration of 5%, 10%, 15%, 20%, and 25%. The positive control used was clorhexidine 0,2% and the negative control was aquadest. The inhibition test of soursop leaf extract were measured using Kirby-Bauer discs method. Data were analyzed with One Way ANOVA and followed by Post-Hoc Turkey HSD. Results: The results showed that the soursop leaf extract have antibacterial activity at concentrations of 25% with inhibitory diameter of 2,0125 mm and 20% with inhibitory diameter of 1,35 mm, but the concentrations of 15%, 10%, and 5% have no inhibition zone against S. sanguinis. There were significant difference in 25% and 20% to 5%, 10%, 15% extract treatment group, control negative and positive control treatment group to 5%, 10%, 15%, 20%, 25% extract treatment group, control negative (p<0,05). Conclusion: Soursop leaf extract with concentrations of 20% and 25% have antibacterial activity against S. sanguinis bacteria growth. Keywords: anti-bacterial agents, Annona, Streptococcus sanguis

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: agen antibakteri, Annona, Streptococcus sanguis
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
R Medicine > RK Dentistry > RK60.7-60.8 Preventive dentistry
Divisions: Faculty of Medicine > 12201-Dentistry (S1)
Depositing User: R.A.Muthiah Nurazimah
Date Deposited: 24 Nov 2020 02:48
Last Modified: 24 Nov 2020 02:48
URI: http://repository.unsri.ac.id/id/eprint/37873

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