DI-(2-ETHYLHEXYL)PHTHALATE AND PYRANON DERIVATED FROM ENDOPHYTIC FUNGI Penicillium sp THE LEAVE OF KUNYIT PUTIH (Curcuma zedoaria)

Fitrya, Fitrya (2014) DI-(2-ETHYLHEXYL)PHTHALATE AND PYRANON DERIVATED FROM ENDOPHYTIC FUNGI Penicillium sp THE LEAVE OF KUNYIT PUTIH (Curcuma zedoaria). Indonesian Journal of Chemistry, 14 (3). pp. 290-296. ISSN 1411-9420

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Abstract

Two compounds from cultivation of the endophytic fungi Penicillium sp of leaves of kunyit putih (Curcuma zedoaria have been isolated. The endophytic fungus was cultivated on 5 L of Potatos Dextrose Broth (PDB) medium at room temperature (no shaking) for 3 weeks. The cultures were extracted with ethyl acetate to afford 3.0 g of residue after removal of the solvent under reduced pressure. The extract was separated and purified by silica gel column chromatography (CC) and afforded two pure compounds as colorless oily liquid (compound 1) and yellow crystal (compound 2). The structure of these compounds were characterized by detailed UV, IR, and NMR spectroscopic analysis and compound 1 as well as comparison with the reported data. Base on spectra analysis the compound 1 was determined as Di-(2-ethylhexyl)phthalate and compound 2 as 5-(4’-ethoxy-2’-hydroxy-5’-methyl- 2’,3’-dihydrofuran-3’-il (hydroxy) methyl-4-isopropyl-3-methyl-2-pyran-2-on). Compound 1 is not new compound, but it is new for endophytic fungus from C. zeodoria and compound 2 is new compound.

Item Type: Article
Subjects: #3 Repository of Lecturer Academic Credit Systems (TPAK) > Hak Atas Kekayaan Intelektual (HAKI)-PATENT
Divisions: 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: M.Si, Apt. Fitrya Fitrya
Date Deposited: 06 Jan 2021 02:42
Last Modified: 06 Jan 2021 02:42
URI: http://repository.unsri.ac.id/id/eprint/38990

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