HUBUNGAN PENGGUNAAN KORTIKOSTEROID PADA PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS TERHADAP KEJADIAN KATARAK DI RUMAH SAKIT MOHAMMAD HOESIN

SUNARDI, BRIZKA and Iskandar, Elza and Tamzil, Nia Savitri (2020) HUBUNGAN PENGGUNAAN KORTIKOSTEROID PADA PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS TERHADAP KEJADIAN KATARAK DI RUMAH SAKIT MOHAMMAD HOESIN. Undergraduate thesis, Sriwijaya University.

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Abstract

Background. Cataracts are clouding that occurs in the lens of the eye due to lens hydration, protein denaturation, or both. Cataracts can occur multifactorial, one of which is the use of corticosteroid drugs. Systemic Lupus Erythematosus is a disease that uses long-term corticosteroids as a treatment option. The increasing number of SLE sufferers will increase long-term use of corticosteroids, so it is feared that the incidence of cataracts will increase. This study aims to determine the relationship between the use of corticosteroids in patients with Systemic Lupus Erythematosus and the incidence of cataracts at Mohammad Hosein Hospital. Methods. This study was an analytic observational study with a cross sectional design. This data was taken from the medical records of Systemic Lupus Erythematosus patients at Mohammad Hoesin Hospital for the period January 2019-December 2019. Results. Of 198 cases. There were 37 cases (18.7%) had cataracts and 161 cases (81.3%) had no cataracts. All patients with cataracts used corticosteroids for ≥12 months. Patients taking doses ≥10mg/day had a greater risk than <10mg/day There was a significant relationship between the duration of corticosteroid use (p=0.001) and corticosteroid dose (p=0.001) on the incidence of cataracts.. Conclusion. The duration of corticosteroid usage and corticosteroid dose have a significant association with the incidence of cataracts. Keyword: cataracts, corticosteroids, Systemic Lupus Erythematosus

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: katarak, kortikosteroid, Systemic Lupus Erythematosus
Subjects: R Medicine > R Medicine (General) > R702-703 Medicine and the humanities. Medicine and disease in relation to history, literature, etc.
R Medicine > R Medicine (General) > R728-733 Practice of medicine. Medical practice economics
R Medicine > R Medicine (General) > R864 Medical records
R Medicine > RC Internal medicine > RC581-607 Immunologic diseases. Allergy
R Medicine > RE Ophthalmology > RE1-994 Ophthalmology
R Medicine > RE Ophthalmology > RE80-87 Eye surgery
R Medicine > RE Ophthalmology > RE991-992 Ocular therapeutics
Divisions: Faculty of Medicine > 11201-Medicine (S1)
Depositing User: Brizka Sunardi
Date Deposited: 13 Jan 2021 03:21
Last Modified: 13 Jan 2021 03:21
URI: http://repository.unsri.ac.id/id/eprint/39920

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