PENGARUH PEMBERIAN EKSTRAK IKAN PATIN SIAM TERHADAP SEL FIBROBLAS PASCA EKSTRAKSI GIGI TIKUS WISTAR

Ricardo, Angelina Natalia and K, Trisnawaty and Larasati, Veny (2020) PENGARUH PEMBERIAN EKSTRAK IKAN PATIN SIAM TERHADAP SEL FIBROBLAS PASCA EKSTRAKSI GIGI TIKUS WISTAR. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Tooth extraction is a common treatment procedure that result in the formation of wound. Nutrition is one of the factors that influence wound healing. Siamese catfish is a source of nutrition, but its effect in wound healing process is still unknown. Objective: To determine the effect of administration of Siamese catfish extract orally on the number of fibroblast cells in wound healing after tooth extraction of Wistar rats. Methods: This research was true experimental laboratory with posttest only control group design. 24 male Wistar rat were divided into 6 groups. After the mandibular left incisor was extracted, rats in groups 1, 2, and 3 were given Siamese catfish extract and groups 4, 5, and 6 were given aquadest orally once a day. Groups 1 and 4 were treated for 3 days, groups 2 and 5 were treated for 5 days, and groups 3 and 6 were treated for 7 days, then the rats were euthanized and made histological preparations. Fibroblast cells were calculated using Image Raster software and analyzed using One Ways ANOVA and Post Hoc LSD tests. Results: The number of fibroblast cells increased on the the 5th day and reached the highest number on the 7th day. ANOVA test showed a significant difference in the mean of fibroblast number between the treatment and control groups (p<0,05). However, the Post Hoc test showed that there was not significant difference (p>0,05) between Siamese catfish extract and aquadest groups on the 3rd day. Conclusion: The administration of Siamese catfish extract orally can increase the number of fibroblast cells in wound healing after tooth extraction of Wistar rats.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: fibroblas, ikan patin siam, penyembuhan luka
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
R Medicine > RK Dentistry > RK529-535 Oral surgery
Divisions: Faculty of Medicine > 12201-Dentistry (S1)
Depositing User: Angelina Natalia Ricardo
Date Deposited: 14 Jan 2021 06:16
Last Modified: 14 Jan 2021 06:16
URI: http://repository.unsri.ac.id/id/eprint/40050

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