KARAKTERISTIK KLINIS DAN LABORATORIS PASIEN BARU TALASEMIA DI BAGIAN ANAK RSUP DR. MOHAMMAD HOESIN PALEMBANG

RAHMAH, KAMILA and Sari, Dian Puspita and Ayu, Dewi Rosariah (2018) KARAKTERISTIK KLINIS DAN LABORATORIS PASIEN BARU TALASEMIA DI BAGIAN ANAK RSUP DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Thalassemia is hereditary blood disosders caused by decreased or absence of synthesis α-globin or β-globin chains. Patients come with variety of clinical manifestation and laboratory findings. Goal of this study is to review clinical manifestation and clinical laboratory of new thalassemia patients at pediatrics department of RSUP Dr. Mohammad Hoesin Palembang. Methods: This study was a descriptive study. The population and sample in this study were all new thalassemia patients in RSUP Dr. Mohammad Hoesin Palembang period January 1st 2015 until July 31st 2017. Result: A total of 48 subjects, most of them were 0-5 years old (68,7%), normal nutritional status (52,1%), normal stature (54,2%), pale, micrositic hypocromic, thalassemia-β. Subject with same history of thalassemia in the family (31,3%). Mean of Hb was 6,9±2,2g/dL, Ht was 22±7%, MCV was 68,1±8,7fL, MCH was 22±5pg, MCHC was 32±4g/dL, RBC was 3,27±1,14 106/mm3, retikulosit was 3,9±2,4%, SI was 128±73μg/L, TIBC was 214±75μg/dL, transferin was 62%, Ferritin was 470,94±461,78μg/mL, HbA2 was 11,6±18,4%, HbF was 25,1±21,4%. Conclusion: Most of subjects were normal stature, pale, micrositic hypocromic, thalassemia-β. Mean of Hb, Ht, MCV, MCH, RBC were below the normal value. Reticulocyt, transferrin, ferritin, HbA2 and HbF were above the normal value. MCHC, SI and TIBC were at normal value.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Thalassemia, characteristics, manifestations, laboratory
Subjects:	R Medicine > RB Pathology > RB127-150 Manifestations of disease
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Mrs Furika Furika
Date Deposited:	12 Aug 2019 05:18
Last Modified:	12 Aug 2019 05:18
URI:	http://repository.unsri.ac.id/id/eprint/4129

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