Effect Of Pomegranate (Punica granatum L.) Fraction In Reducing Total Blood Cholesterol Levels and Triglyceride in Mice (Mus muscullus L.)

Agustini, Nurlaily and Setiawan, Arum and Salni, Salni (2020) Effect Of Pomegranate (Punica granatum L.) Fraction In Reducing Total Blood Cholesterol Levels and Triglyceride in Mice (Mus muscullus L.). Indonesian Journal of Environmental Management and Sustainability, 4 (1). pp. 14-22. ISSN e-ISSN:2598-6279p-ISSN:2598-6260

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Abstract

Pomegranate (Punica granatum L.) will be examined by looking at the ability between pomegranate extracts or fractions, which are more effective in lowering total blood cholesterol and triglyceride levels in mice. This study aims to determine the effect pomegranate fraction of methanol water from several concentrate that can reduce the total cholesterol levels and triglyceride in mice. The research method used was an experimental method with a completely randomized design (CRD) pattern. The research used 6 treatment groups, and test animals divided into 6 treatment groups namely negative control given aquades, positive control fed a high-fat diet, given simvastatin, given 25 mg/grBB pomegranate fraction of methanol water, given 50 mg/grBB pomegranate fraction of methanol water, given 100 mg/grBB of pomegranate fraction of methanol water, each treatment group will be divided into 4 male mice. Based on the results of this study, the active fraction that has an effect on reducing blood cholesterol and triglyceride levels with a percentage reduction about 48% and the significance value of 0,000 <α = 0.05 is the treatment given 100mg/grBB pomegranate fraction of methanol water.

Item Type: Article
Additional Information: Jurnal Nasional Terakreditasi (Sinta 3)
Subjects: Q Science > QL Zoology
Q Science > QM Human anatomy
Q Science > QP Physiology
Q Science > QP Physiology > QP(901)-(981) Experimental pharmacology
Divisions: 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1)
Depositing User: Dr Arum Setiawan
Date Deposited: 04 Feb 2021 00:42
Last Modified: 04 Feb 2021 00:42
URI: http://repository.unsri.ac.id/id/eprint/41866

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