Liberty, Iche Andriyani (2020) Association Between Triglyceride-Glucose Index (TyG Index) and Type 2 Diabetes Mellitus: A Systematic Review. Epidemiology Biostatistics and Public Health, 17 (1). pp. 1-6. ISSN 22820930, 22822305
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Abstract
Background: Insulin Resistance has a major role in the pathogenesis of diabetes mellitus where there is a decrease in sensitivity in peripheral tissues. The emergence of insulin resistance, 1-2 decades precedes before the diagnosis of type 2 diabetes mellitus is established. This theory is supported by the usefulness of insulin resistance as a marker of future diabetes or the prevention of type 2 diabetes by insulin-sensitizing agents. Recently, there is evidence that has been suggested to measure insulin resistance as surrogate marker by calculated the triglyceride and glucose which is so called as “Fasting triglyceride-glucose index” or can be shorten as “TyG index”. This study reported a systematic review of association between TyG index and type 2 diabetes mellitus from various literatures to make a conclusion as a basis for further research. Methods: A literature search in EBSCOhost, ProQuest, MEDLINE, and NCBI database was performed to retrieve and review studies reporting the association between TyG index and type 2 diabetes. Results: All studies showed that higher TyG index were associated with higher type 2 diabetes (HR 4.36, 10.38, 9.54 for each). Conclusion: This systematic review provides further evidence about higher TyG index is related to higher risk of development type 2 diabetes. It represents that TyG index can predicting the risk of incident T2DM. Key words: TyG index, Triglyceride Glucose Index, T2DM, Type 2 Diabetes Mellitus
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection |
| Divisions: | 04-Faculty of Medicine > 11201-Medicine (S1) |
| Depositing User: | Dr Iche Andriyani Liberty |
| Date Deposited: | 28 Feb 2021 05:54 |
| Last Modified: | 28 Feb 2021 05:54 |
| URI: | http://repository.unsri.ac.id/id/eprint/42419 |
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